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Difference between revisions of "SMARCA4-deficient non-small cell carcinoma of the lung"
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SMARCA4-deficient non-small cell carcinoma of the lung (view source)
Revision as of 19:18, 24 October 2019
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*Hepatoid [[adenocarcinoma of lung]] shows cytoplasmic [[TTF-1]] staining.<ref name=pmid24030743>{{Cite journal | last1 = Haninger | first1 = DM. | last2 = Kloecker | first2 = GH. | last3 = Bousamra Ii | first3 = M. | last4 = Nowacki | first4 = MR. | last5 = Slone | first5 = SP. | title = Hepatoid adenocarcinoma of the lung: report of five cases and review of the literature. | journal = Mod Pathol | volume = 27 | issue = 4 | pages = 535-42 | month = Apr | year = 2014 | doi = 10.1038/modpathol.2013.170 | PMID = 24030743 }}</ref> | *Hepatoid [[adenocarcinoma of lung]] shows cytoplasmic [[TTF-1]] staining.<ref name=pmid24030743>{{Cite journal | last1 = Haninger | first1 = DM. | last2 = Kloecker | first2 = GH. | last3 = Bousamra Ii | first3 = M. | last4 = Nowacki | first4 = MR. | last5 = Slone | first5 = SP. | title = Hepatoid adenocarcinoma of the lung: report of five cases and review of the literature. | journal = Mod Pathol | volume = 27 | issue = 4 | pages = 535-42 | month = Apr | year = 2014 | doi = 10.1038/modpathol.2013.170 | PMID = 24030743 }}</ref> | ||
==Sign out== | |||
<pre> | |||
The tumour stains as follows: | |||
POSITIVE: CK7 (diffuse, strong), HepPar-1 (strong, diffuse). | |||
NEGATIVE: TTF-1, napsin A, p63, CK5/6. | |||
The staining pattern for this tumour is not typical for lung adenocarcinoma; please correlate with the clinical findings. | |||
HepPar-1 POSITIVITY with CK7 POSITIVITY and TTF-1 NEGATIVITY may be seen in SMARCA4-deficient adenocarcinoma of the lung.[1] | |||
1. Virchows Arch 471 (5): 599-609. doi:10.1007/s00428-017-2148-5. PMID 28555282. | |||
</pre> | |||
==See also== | ==See also== | ||