Difference between revisions of "Olfactory neuroblastoma"

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→‎IHC: differences based on mutation status
(Molecular Data added)
(→‎IHC: differences based on mutation status)
Line 41: Line 41:
**Small round cells -ve.
**Small round cells -ve.
*[[Neuroendocrine markers]] +ve (CD56, synaptophysin).
*[[Neuroendocrine markers]] +ve (CD56, synaptophysin).
**lower expression of neuroendocrine markers in IDH2 mutant tumors.


Others:
Others:
Line 46: Line 47:
*AE1/AE3 usu. -ve (r/o carcinoma).
*AE1/AE3 usu. -ve (r/o carcinoma).
*CAM5.2 usu. -ve -- up to 35% +ve.<ref name=Ref_WMSP41>{{Ref WMSP|41}}</ref>
*CAM5.2 usu. -ve -- up to 35% +ve.<ref name=Ref_WMSP41>{{Ref WMSP|41}}</ref>
**Higher expression of cytokeratins in IDH2 mutant tumors.


==Molecular==
==Molecular==
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