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*CK7 and CK20 variable.<ref name=pmid22461652>{{Cite journal | last1 = Matsukuma | first1 = KE. | last2 = Montgomery | first2 = EA. | title = Tubular carcinoids of the appendix: the CK7/CK20 immunophenotype can be a diagnostic pitfall. | journal = J Clin Pathol | volume = 65 | issue = 7 | pages = 666-8 | month = Jul | year = 2012 | doi = 10.1136/jclinpath-2011-200639 | PMID = 22461652 }}</ref> | *CK7 and CK20 variable.<ref name=pmid22461652>{{Cite journal | last1 = Matsukuma | first1 = KE. | last2 = Montgomery | first2 = EA. | title = Tubular carcinoids of the appendix: the CK7/CK20 immunophenotype can be a diagnostic pitfall. | journal = J Clin Pathol | volume = 65 | issue = 7 | pages = 666-8 | month = Jul | year = 2012 | doi = 10.1136/jclinpath-2011-200639 | PMID = 22461652 }}</ref> | ||
==Sign out== | |||
<pre> | |||
Vermiform Appendix, Appendectomy: | |||
- Low-grade neuroendocrine tumour (carcinoid tumour), see comment. | |||
-- Margins clear. | |||
-- Please see synoptic report. | |||
- Perforated acute appendicitis with periappendicitis. | |||
Comment: | |||
The tumour stains as follows: | |||
POSITIVE: AE1/AE3, chromogranin A, synaptophysin, CD56. | |||
NEGATIVE: CK7, CK20, S100. | |||
PROLIFERATION (Ki-67): <3%. | |||
The low-grade neuroendocrine tumour (in the planes of section) is in the tip and | |||
separate from the appendiceal perforation site/acute appendicitis. | |||
</pre> | |||
==See also== | ==See also== |
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