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Difference between revisions of "Oligodendroglioma"
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→Histologic grading: IDH1 and 2
Jensflorian (talk | contribs) (→Molecular pathology: IDH and LOH required) |
Jensflorian (talk | contribs) (→Histologic grading: IDH1 and 2) |
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# WHO grade II. | # WHO grade II. | ||
#*This is most oligodendrogliomas. | #*This is most oligodendrogliomas. | ||
#*Without genetic testing for [[IDH-1]] and LOH 1p/19q, the tumor is called Oligodendroglioma, NOS. | #*Without genetic testing for [[IDH-1]]/2 and LOH 1p/19q, the tumor is called Oligodendroglioma, NOS. | ||
# WHO grade III. | # WHO grade III. | ||
#*Features for calling high grade:<ref name=Ref_PSNP98>{{Ref PSNP|98}}</ref> | #*Features for calling high grade:<ref name=Ref_PSNP98>{{Ref PSNP|98}}</ref> | ||
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#**Necrosis. | #**Necrosis. | ||
#**High mitotic rate (6 mitoses/10 HPF for whatever "HPF" means, see [[HPFitis]]). | #**High mitotic rate (6 mitoses/10 HPF for whatever "HPF" means, see [[HPFitis]]). | ||
#*Without genetic testing for [[IDH-1]] and LOH 1p/19q, the tumor is called Anaplastic oligodendroglioma, NOS. | #*Without genetic testing for [[IDH-1]]/2 and LOH 1p/19q, the tumor is called Anaplastic oligodendroglioma, NOS. | ||
==IHC== | ==IHC== | ||