Difference between revisions of "Neurodegenerative diseases"

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* Lewy bodies and extracellular pigment in neuromelanin-containing nuclei (SN, LC, DVN) -> PD.
* Lewy bodies and extracellular pigment in neuromelanin-containing nuclei (SN, LC, DVN) -> PD.
* Spongiform vacuolation in the neuropil (seen in Prion disease).
* Spongiform vacuolation in the neuropil (seen in Prion disease and FTLD-TDP).
* Neurofibrillar tangles (pyramidal layer of dentate gyrus).
* Granulovacuolar degeneration (granules within cytoplasmic vacuoles, mainly in the hippocampal pyramidal neurons, seen in AD).
* Cores of amyloid plaqyes.  
* Cotton wool plaques (seen in familiar AD).
* Cotton wool plaques (seen in familiar AD).
* Pick cells (balloned neurons in frontal cortex).
* Pick bodies (granular layer of dentate gyrus).
* Extensive astrogliosis (striatonigral degeneration, hepatic encephalopathy).
* Corpora amylacea in the cornu ammonis may be increased in neurodegenerative diseases. <ref>{{Cite journal  | last1 = Kovacs | first1 = GG. | last2 = Risser | first2 = D. | title = Clinical Neuropathology image 6-2014: Corpora amylacea replacing cornu ammonis (CACA). | journal = Clin Neuropathol | volume = 33 | issue = 6 | pages = 378-9 | month =  | year =  | doi =  | PMID = 25343241 }}</ref>
* Corpora amylacea in the cornu ammonis may be increased in neurodegenerative diseases. <ref>{{Cite journal  | last1 = Kovacs | first1 = GG. | last2 = Risser | first2 = D. | title = Clinical Neuropathology image 6-2014: Corpora amylacea replacing cornu ammonis (CACA). | journal = Clin Neuropathol | volume = 33 | issue = 6 | pages = 378-9 | month =  | year =  | doi =  | PMID = 25343241 }}</ref>


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