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→TDP Proteinopathies: IHC
Jensflorian (talk | contribs) (→TDP Proteinopathies: update) |
Jensflorian (talk | contribs) (→TDP Proteinopathies: IHC) |
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=TDP Proteinopathies= | =TDP Proteinopathies= | ||
==FTLD-TDP== | |||
*Accounts for about 50% of all FTLD cases. | *Accounts for about 50% of all FTLD cases. | ||
*Degeneration of frontal and temporal lobes. | |||
*Inclusions not seen in HE or silver stains. | |||
*TDP43-positive | *TDP43-positive | ||
**Neuronal cytoplasmic inclusions. | **Neuronal cytoplasmic inclusions. | ||
**Neuronal intranuclear inclusions. | **Neuronal intranuclear inclusions. | ||
**Dystrophic neurites. | **Dystrophic neurites. | ||
*Ubiquitin+ve. | |||
*p62+ve. | |||
*aSynculein-ve. | |||
*Tau-ve. | |||
*FUS-ve. | |||
=FTLD-FET= | =FTLD-FET= | ||