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*LN sampling is associated with morbidity; thus, selective LN sampling is preferred. | *LN sampling is associated with morbidity; thus, selective LN sampling is preferred. | ||
*The most important LNs in a LN chain, in the context of [[cancer]], are the ones that are adjacent to the tumour; these are known as '''sentinel lymph nodes'''. | *The most important LNs in a LN chain, in the context of [[cancer]], are the ones that are adjacent to the tumour; these are known as '''sentinel lymph nodes'''. | ||
*In lymph node positive disease, the most radioactive lymph node may be negative; this happens ~13% of the time in melanoma.<ref name=pmid11314933>{{Cite journal | last1 = McMasters | first1 = KM. | last2 = Reintgen | first2 = DS. | last3 = Ross | first3 = MI. | last4 = Wong | first4 = SL. | last5 = Gershenwald | first5 = JE. | last6 = Krag | first6 = DN. | last7 = Noyes | first7 = RD. | last8 = Viar | first8 = V. | last9 = Cerrito | first9 = PB. | title = Sentinel lymph node biopsy for melanoma: how many radioactive nodes should be removed? | journal = Ann Surg Oncol | volume = 8 | issue = 3 | pages = 192-7 | month = Apr | year = 2001 | doi = | PMID = 11314933 }}</ref> | |||
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