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Difference between revisions of "Medical lung diseases"
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→Pulmonary alveolar proteinosis: +image
(→Lymphangioleiomyomatosis: more) |
(→Pulmonary alveolar proteinosis: +image) |
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==Pulmonary alveolar proteinosis== | ==Pulmonary alveolar proteinosis== | ||
*Abbreviated ''PAP''. | *Abbreviated ''PAP''. | ||
===General=== | |||
*Associated with smoking - particularily in men.<ref name=pmid14695413>{{cite journal |author=Trapnell BC, Whitsett JA, Nakata K |title=Pulmonary alveolar proteinosis |journal=N. Engl. J. Med. |volume=349 |issue=26 |pages=2527-39 |year=2003 |month=December |pmid=14695413 |doi=10.1056/NEJMra023226 |url=http://content.nejm.org/cgi/content/extract/349/26/2527}}</ref> | *Associated with smoking - particularily in men.<ref name=pmid14695413>{{cite journal |author=Trapnell BC, Whitsett JA, Nakata K |title=Pulmonary alveolar proteinosis |journal=N. Engl. J. Med. |volume=349 |issue=26 |pages=2527-39 |year=2003 |month=December |pmid=14695413 |doi=10.1056/NEJMra023226 |url=http://content.nejm.org/cgi/content/extract/349/26/2527}}</ref> | ||
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*Dyspnea & cough - gradual onset. | *Dyspnea & cough - gradual onset. | ||
===Radiology=== | ====Radiology==== | ||
*CXR: airspace disease. | *CXR: airspace disease. | ||
*HRCT: "crazy paving" - see: [http://radiographics.rsnajnls.org/cgi/content/figsonly/23/6/1509 http://radiographics.rsnajnls.org/cgi/content/figsonly/23/6/1509]. | *HRCT: "crazy paving" - see: [http://radiographics.rsnajnls.org/cgi/content/figsonly/23/6/1509 http://radiographics.rsnajnls.org/cgi/content/figsonly/23/6/1509]. | ||
=== | ===Microscopic=== | ||
*Crap in alveoli | Features: | ||
*Crap in the alveoli: | |||
*"Dense bodies" - dead macrophages ("Chatter" in the alveoli). | *"Dense bodies" - dead macrophages ("Chatter" in the alveoli). | ||
**Edema - has pink stuff in the alveoli like PAP but no ''dense bodies''. | **Edema - has pink stuff in the alveoli like PAP but no ''dense bodies''. | ||
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*Edema. | *Edema. | ||
*Pneumocystis. | *Pneumocystis. | ||
Images: | |||
*[http://jcp.bmjjournals.com/content/62/5/387/F23.large.jpg PAP (bmjjournals.com)].<ref name=pmid19398592>{{cite journal |author=Leslie KO |title=My approach to interstitial lung disease using clinical, radiological and histopathological patterns |journal=J. Clin. Pathol. |volume=62 |issue=5 |pages=387–401 |year=2009 |month=May |pmid=19398592 |pmc=2668105 |doi=10.1136/jcp.2008.059782 |url=}}</ref> | |||
==Drug reactions== | ==Drug reactions== | ||