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Difference between revisions of "Primary mediastinal B-cell lymphoma"
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Primary mediastinal B-cell lymphoma (view source)
Revision as of 21:21, 16 June 2018
, 21:21, 16 June 2018DLBCL vs PMBCL
(a few points) |
m (DLBCL vs PMBCL) |
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| Line 7: | Line 7: | ||
*Rare. | *Rare. | ||
*Young adults, more common in females (M:F = 1:2) | *Young adults, more common in females (M:F = 1:2) | ||
*[[Mediastinum]]. | *[[Mediastinum]] | ||
It is distinguished from DLBCL based on the patient demographics, radiological staging (showing mainly mediastinal disease) and immunoprofile (typically CD23+/CD30+). PMBCL has a better prognosis than DLBCL. | |||
==Microscopic== | ==Microscopic== | ||
Features: | Features: | ||
*Atypical large lymphoid cells - | *Atypical large lymphoid cells - may be morphologically indistinguishable from ''[[DLBCL]]'' | ||
*Classically associated with: | *Classically associated with: | ||
**Fibrosis | **Fibrosis | ||