Difference between revisions of "Acute myeloid leukemia"

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*t(8;21)(q22;q22).<ref>{{Cite journal  | last1 = Berger | first1 = R. | title = Translocation t(8;21)(q22;q22): cytogenetics and molecular biology. | journal = Nouv Rev Fr Hematol | volume = 36 Suppl 1 | issue =  | pages = S67-9 | month =  | year = 1994 | doi =  | PMID = 8177719 }}</ref>
*t(8;21)(q22;q22).<ref>{{Cite journal  | last1 = Berger | first1 = R. | title = Translocation t(8;21)(q22;q22): cytogenetics and molecular biology. | journal = Nouv Rev Fr Hematol | volume = 36 Suppl 1 | issue =  | pages = S67-9 | month =  | year = 1994 | doi =  | PMID = 8177719 }}</ref>


IHC:
===IHC===
*CD34+, CD13+, MPO+ (cytoplasm), CD33+ (weak).
*CD34+, CD13+, MPO+ (cytoplasm), CD33+ (weak).
*[[CD56]]+, CD117+.  
*[[CD56]]+, CD117+.  
**Usu. assoc. with a bad prognosis.
**Usu. assoc. with a bad prognosis.


Flow cytometry:
===Flow cytometry===
*CD19+, PAX5+, CD79a +/-.
*CD19+, PAX5+, CD79a +/-.


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*Associated with [[myeloid sarcoma]].
*Associated with [[myeloid sarcoma]].


Microscopic:
===Microscopic===
*Blast count usu. ~20% (low).
*Blast count usu. ~20% (low).
*Eosinophilic granules.
*Eosinophilic granules.
**Used to be classified as "M4" with eosinophilia.
**Used to be classified as "M4" with eosinophilia.


IHC:
===IHC===
*CD2+ -- common.
*CD2+ -- common.


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