Difference between revisions of "Pseudoinvasion in colorectal adenomatous polyps"

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(→‎Microscopic: +adenoma-like adenocarcinoma)
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*[[Gastrointestinal_tract_polyps#Colorectal_adenocarcinoma|Colorectal adenocarcinoma]].
*[[Gastrointestinal_tract_polyps#Colorectal_adenocarcinoma|Colorectal adenocarcinoma]].
**Adenoma-like adenocarcinoma.<ref name=pmid25913616>{{Cite journal  | last1 = Gonzalez | first1 = RS. | last2 = Cates | first2 = JM. | last3 = Washington | first3 = MK. | last4 = Beauchamp | first4 = RD. | last5 = Coffey | first5 = RJ. | last6 = Shi | first6 = C. | title = Adenoma-like adenocarcinoma: a subtype of colorectal carcinoma with good prognosis, deceptive appearance on biopsy and frequent KRAS mutation. | journal = Histopathology | volume = 68 | issue = 2 | pages = 183-90 | month = Jan | year = 2016 | doi = 10.1111/his.12725 | PMID = 25913616 }}</ref>
**Adenoma-like adenocarcinoma.<ref name=pmid25913616>{{Cite journal  | last1 = Gonzalez | first1 = RS. | last2 = Cates | first2 = JM. | last3 = Washington | first3 = MK. | last4 = Beauchamp | first4 = RD. | last5 = Coffey | first5 = RJ. | last6 = Shi | first6 = C. | title = Adenoma-like adenocarcinoma: a subtype of colorectal carcinoma with good prognosis, deceptive appearance on biopsy and frequent KRAS mutation. | journal = Histopathology | volume = 68 | issue = 2 | pages = 183-90 | month = Jan | year = 2016 | doi = 10.1111/his.12725 | PMID = 25913616 }}</ref>
==IHC===
*MMP-1, p53, E-cadherin, collagen IV - may have some utility.<ref name=pmid11812942>{{Cite journal  | last1 = Yantiss | first1 = RK. | last2 = Bosenberg | first2 = MW. | last3 = Antonioli | first3 = DA. | last4 = Odze | first4 = RD. | title = Utility of MMP-1, p53, E-cadherin, and collagen IV immunohistochemical stains in the differential diagnosis of adenomas with misplaced epithelium versus adenomas with invasive adenocarcinoma. | journal = Am J Surg Pathol | volume = 26 | issue = 2 | pages = 206-15 | month = Feb | year = 2002 | doi =  | PMID = 11812942 }}</ref>
**Probably not useful for difficult cases.


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