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| *[[AKA]] ''pseudoinvasion''. | | *[[AKA]] ''pseudoinvasion''. |
| *[[AKA]] ''epithelial misplacement''. | | *[[AKA]] ''epithelial misplacement''. |
| ===General===
| | {{Main|Pseudoinvasion in colorectal adenomatous polyps}} |
| *Mimic of invasion.
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| *Pedunculated polyps.<ref>{{Cite journal | last1 = Byun | first1 = TJ. | last2 = Han | first2 = DS. | last3 = Ahn | first3 = SB. | last4 = Cho | first4 = HS. | last5 = Eun | first5 = CS. | last6 = Jeon | first6 = YC. | last7 = Sohn | first7 = JH. | last8 = Oh | first8 = YH. | title = Pseudoinvasion in an adenomatous polyp of the colon mimicking invasive colon cancer. | journal = Gut Liver | volume = 3 | issue = 2 | pages = 130-3 | month = Jun | year = 2009 | doi = 10.5009/gnl.2009.3.2.130 | PMID = 20431736 | PMC = PMC2852693 | URL = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852693/ }}</ref>
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| *Left-sided lesions, esp. sigmoid colon.<ref name=Ref_Odze512>{{Ref Odze|512}}</ref>
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| | |
| ===Microscopic===
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| Features - classic:<ref name=pmid4540378>{{Cite journal | last1 = Muto | first1 = T. | last2 = Bussey | first2 = HJ. | last3 = Morson | first3 = BC. | title = Pseudo-carcinomatous invasion in adenomatous polyps of the colon and rectum. | journal = J Clin Pathol | volume = 26 | issue = 1 | pages = 25-31 | month = Jan | year = 1973 | doi = | PMID = 4540378 | PMC = 477644 | URL = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC477644/?tool=pubmed }}</ref>
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| #Dysplastic glands surrounded by lamina propria.
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| #Hemosiderin.
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| #Lack of [[desmoplastic reaction]].
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| *+/-Cystic spaces with rounded contours without cells floating in them.
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| | |
| Memory device (classic features) ''LDH'':
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| *'''L'''amina propria.
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| *'''D'''esmoplasia lacking.
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| *'''H'''emosiderin.
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| DDx:
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| *[[Gastrointestinal_tract_polyps#Colorectal_adenocarcinoma|Colorectal adenocarcinoma]].
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| | |
| ===Sign out===
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| Note:
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| *The term ''pseudoinvasion'' may be confusing to clinicians.
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| | |
| <pre>
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| COLON POLYP, SIGMOID COLON AT 45 CM, EXCISION:
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| - TUBULAR ADENOMA.
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| -- NEGATIVE FOR HIGH-GRADE DYSPLASIA.
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| - SUBMUCOSA PRESENT, NO EVIDENCE OF INVASION.
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| - ABUNDANT HEMOSIDERIN-LADEN MACROPHAGES.
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| </pre>
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| | |
| ====Alternate====
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| <pre>
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| POLYP, SIGMOID COLON, EXCISION:
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| - LARGE TUBULAR ADENOMA.
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| -- NEGATIVE FOR HIGH-GRADE DYSPLASIA.
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| - SCANT BENIGN SUBMUCOSA.
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| - DEEP HEMOSIDERIN-LADEN MACROPHAGES.
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| </pre>
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|
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|
| ==High-risk features in (colorectal) adenomatous polyps with carcinoma== | | ==High-risk features in (colorectal) adenomatous polyps with carcinoma== |