Difference between revisions of "Spitz nevus"

Spitz nevus (view source)

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 *+/-[[Acanthosis]] (thick stratum spinosum).
 *Kamino bodies (also written ''Camino bodies'') - dense eosinophilic bodies.<ref name=PMC2797485>{{Cite journal  | last1 = Kirkwood | first1 = John M. | last2 = Jukic | first2 = Drazen | last3 = Averbook | first3 = Bruce J. | last4 = Sender | first4 = Leonard S. | title = Melanoma in Pediatric, Adolescent, and Young Adult Patients | journal = Semin Oncol. | volume = 36 | issue = 5 | pages = 419-31 | month = October | year = 2009 | doi =  | PMID =  | URL = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797485/?tool=pmcentrez |PMC = 2797485 }}</ref>
-**Apoptotic cells.
 **Kamino bodies are rare in melanoma.
+**Pathogenesis uncertain - the classic teachng is Kamino bodies are apoptotic cells; however, this is disputed.<ref name=pmid9855350>{{Cite journal  | last1 = Wesselmann | first1 = U. | last2 = Becker | first2 = LR. | last3 = Bröcker | first3 = EB. | last4 = LeBoit | first4 = PE. | last5 = Bastian | first5 = BC. | title = Eosinophilic globules in spitz nevi: no evidence for apoptosis. | journal = Am J Dermatopathol | volume = 20 | issue = 6 | pages = 551-4 | month = Dec | year = 1998 | doi =  | PMID = 9855350 }}</ref>
 Notes:
 *'''Never''' in the setting of [[solar elastosis]].<ref>Jakubovic, H. 16 July 2010.</ref>