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Difference between revisions of "Germ cell tumours"
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→Teratoma: +gonadoblastoma
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(→Teratoma: +gonadoblastoma) |
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**Neuron-specific B tubulin +ve. | **Neuron-specific B tubulin +ve. | ||
**Synaptophysin +ve. | **Synaptophysin +ve. | ||
==Gonadoblastoma== | |||
===General=== | |||
*Abnormal sexual development. | |||
*Often coexist with [[dysgerminoma]]. | |||
===Microscopic=== | |||
Features:<ref name=Ref_PBoD1104>{{Ref PBoD|1104}}</ref><ref>URL: [http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970245-5 http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970245-5]. Accessed on: 8 April 2011.</ref> | |||
*Immature germ cells resembling Sertoli cells or granulosa cells. | |||
**Sertoli cells = moderate cytoplasm in a trabecular or tubular architecture. | |||
**Granulosa cells = form follicle-like structures. | |||
*Primitive germ cells resemble those of a [[dysgerminoma]]. | |||
**Polygonal cells with a central nucleus, squared-off nuclear membrane and clear cytoplasm. | |||
*+/-Calcification (very common). | |||
Images: | |||
*[http://www.webpathology.com/image.asp?n=40&Case=532 Gonadoblastoma - low mag. (webpathology.com)]. | |||
*[http://www.webpathology.com/image.asp?case=532&n=42 Gonadoblastoma - high mag. (webpathology.com)]. | |||
*[http://www.webpathology.com/image.asp?case=532&n=44 Gonadoblastoma - high mag. (webpathology.com)]. | |||
*[http://commons.wikimedia.org/wiki/File:Gonadoblastoma_-_intermed_mag.jpg Gonadoblastoma - intermed. mag. (WC)]. | |||
*[http://commons.wikimedia.org/wiki/File:Gonadoblastoma_-_b_-_high_mag.jpg Gonadoblastoma - high mag. (WC)]. | |||
==See also== | ==See also== | ||