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Difference between revisions of "Clear cell renal cell carcinoma"
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Clear cell renal cell carcinoma (view source)
Revision as of 16:51, 20 October 2017
, 16:51, 20 October 2017→CCRCC versus chromophobe RCC
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*CD117 -ve (+ve in ChRCC). | *CD117 -ve (+ve in ChRCC). | ||
**Aguilar-León ''et al.'' found 8% of CCRCC are CD117 +ve.<ref name=pmid25643775>{{Cite journal | last1 = Aguilar-León | first1 = D. | last2 = Del Ángel-Millán | first2 = G. | last3 = Zepeda-Quiroz | first3 = I. | last4 = Soria-Céspedes | first4 = D. | title = [Immunohistochemical Expression of CD117 (c-kit) in 75 Renal Cell Tumors]. | journal = Gac Med Mex | volume = 150 Suppl 2 | issue = | pages = 156-60 | month = Dec | year = 2014 | doi = | PMID = 25643775 }}</ref> | **Aguilar-León ''et al.'' found 8% of CCRCC are CD117 +ve.<ref name=pmid25643775>{{Cite journal | last1 = Aguilar-León | first1 = D. | last2 = Del Ángel-Millán | first2 = G. | last3 = Zepeda-Quiroz | first3 = I. | last4 = Soria-Céspedes | first4 = D. | title = [Immunohistochemical Expression of CD117 (c-kit) in 75 Renal Cell Tumors]. | journal = Gac Med Mex | volume = 150 Suppl 2 | issue = | pages = 156-60 | month = Dec | year = 2014 | doi = | PMID = 25643775 }}</ref> | ||
**Liu ''et al.'' found ~80% of ChRCC are CD117 +ve.<ref name=pmid17683191/> | |||
*CA9 ([[carbonic anhydrase 9]]) +ve (membranous).<ref name=pmid21677535>{{cite journal |author=Al-Ahmadie HA, Alden D, Fine SW, ''et al.'' |title=Role of immunohistochemistry in the evaluation of needle core biopsies in adult renal cortical tumors: an ex vivo study |journal=Am. J. Surg. Pathol. |volume=35 |issue=7 |pages=949–61 |year=2011 |month=July |pmid=21677535 |doi=10.1097/PAS.0b013e31821e25cd |url=}}</ref> | *CA9 ([[carbonic anhydrase 9]]) +ve (membranous).<ref name=pmid21677535>{{cite journal |author=Al-Ahmadie HA, Alden D, Fine SW, ''et al.'' |title=Role of immunohistochemistry in the evaluation of needle core biopsies in adult renal cortical tumors: an ex vivo study |journal=Am. J. Surg. Pathol. |volume=35 |issue=7 |pages=949–61 |year=2011 |month=July |pmid=21677535 |doi=10.1097/PAS.0b013e31821e25cd |url=}}</ref> | ||
*[[CK7]] -ve (+ve in ChRCC). | *[[CK7]] -ve (+ve in ChRCC). | ||
May also be useful: | |||
*Vimentin +ve. | *Vimentin +ve. | ||
**-ve in ChRCC. | **-ve in ChRCC.<ref name=pmid17683191>{{Cite journal | last1 = Liu | first1 = L. | last2 = Qian | first2 = J. | last3 = Singh | first3 = H. | last4 = Meiers | first4 = I. | last5 = Zhou | first5 = X. | last6 = Bostwick | first6 = DG. | title = Immunohistochemical analysis of chromophobe renal cell carcinoma, renal oncocytoma, and clear cell carcinoma: an optimal and practical panel for differential diagnosis. | journal = Arch Pathol Lab Med | volume = 131 | issue = 8 | pages = 1290-7 | month = Aug | year = 2007 | doi = 10.1043/1543-2165(2007)131[1290:IAOCRC]2.0.CO;2 | PMID = 17683191 }}</ref> | ||
===CCRCC versus [[CCPRCC]]=== | ===CCRCC versus [[CCPRCC]]=== | ||