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Difference between revisions of "Pituitary gland"
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→Pituitary adenoma: ihc
Jensflorian (talk | contribs) (→IHC) |
Jensflorian (talk | contribs) (→Pituitary adenoma: ihc) |
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Classification: | Classification: | ||
#Microadenoma <= 1 cm. | #Microadenoma <= 1 cm. | ||
#Macroadenoma | #Macroadenoma 1-4 cm. | ||
#Giant adenoma > 4cm. | #Giant adenoma > 4cm. | ||
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Imaging: | Imaging: | ||
*Sellar enlargement. | *Sellar enlargement. | ||
*Bone erosion | *Bone erosion, invasive growth esp. cavernous sinus (35-45%). | ||
*Inhomogenous signal in T1w MRI. | *Inhomogenous signal in T1w MRI. | ||
| Line 145: | Line 145: | ||
*Loss of fibrous stroma. | *Loss of fibrous stroma. | ||
**The cells of a normal (anterior) pituitary are nested. | **The cells of a normal (anterior) pituitary are nested. | ||
*Basophilic cells (cortocotrophs). | |||
*Eosinophilic cells(somatotrophs). | |||
Notes: | Notes: | ||
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*Chromogranin A +ve | *Chromogranin A +ve | ||
*Synaptophysin +ve | *Synaptophysin +ve | ||
Note: | |||
Null-cell adenoma must be hormone immunonegative and negative for transcription factors. | |||
===Variants=== | ===Variants=== | ||