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Difference between revisions of "Medulloblastoma"
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→Histologically defined: desmoplastic
Jensflorian (talk | contribs) (→General: inherited diseases) |
Jensflorian (talk | contribs) (→Histologically defined: desmoplastic) |
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*Severe anaplasia. | *Severe anaplasia. | ||
*Polygonal cells. | *Polygonal cells. | ||
====Desmoplastic/nodular variant==== | |||
Features: | |||
*Nodular, reticulin-free zones (pale islands). | |||
**Mitotic activity is reduced. | |||
*Densely packed internodal, reticulin-positive tumor areas. | |||
*Absence of neuroblastic rosettes. | |||
*Neuronal markers (NeuN, Synaptophysin) can be +ve. | |||
===Genetically defined=== | ===Genetically defined=== | ||