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Difference between revisions of "Medulloblastoma"
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*Mostly paediatric population. | *Mostly paediatric population. | ||
*May be seen as a component of [[nevoid basal cell carcinoma syndrome]] (NBCCS). | *May be seen as a component of [[nevoid basal cell carcinoma syndrome]] (NBCCS). | ||
** | **Show molecularly spatially homogeneous transcriptomes, allowing for accurate subgrouping of tumors from a single biopsy.<ref>{{Cite journal | last1 = Morrissy | first1 = AS. | last2 = Cavalli | first2 = FMG. | last3 = Remke | first3 = M. | last4 = Ramaswamy | first4 = V. | last5 = Shih | first5 = DJH. | last6 = Holgado | first6 = BL. | last7 = Farooq | first7 = H. | last8 = Donovan | first8 = LK. | last9 = Garzia | first9 = L. | title = Spatial heterogeneity in medulloblastoma. | journal = Nat Genet | volume = 49 | issue = 5 | pages = 780-788 | month = May | year = 2017 | doi = 10.1038/ng.3838 | PMID = 28394352 }}</ref> | ||
*Commonly spread via cerebrospinal fluid (CSF).<ref>{{Ref APBR|424 Q34}}</ref> | *Commonly spread via cerebrospinal fluid (CSF).<ref>{{Ref APBR|424 Q34}}</ref> | ||
**May be detected in [[CSF cytopathology]] specimens. | **May be detected in [[CSF cytopathology]] specimens. | ||