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Difference between revisions of "Soft tissue lesions"
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→Fibrohistiocytic tumours: more
(→Fibrohistiocytic tumours: more) |
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==Undifferentiated pleomorphic sarcoma== | ==Undifferentiated pleomorphic sarcoma== | ||
*Abbreviated ''UPS''. | *Abbreviated ''UPS''. | ||
*Previously known as ''malignant fibrous histiocytoma''. | *Previously known as ''malignant fibrous histiocytoma''.<ref>URL: [http://sarcomahelp.org/learning_center/mfh.html http://sarcomahelp.org/learning_center/mfh.html]. Accessed on: 8 April 2011.</ref> | ||
===General=== | ===General=== | ||
*Common sarcoma. | *Common sarcoma. | ||
*Usu. deep tissue of the trunk and extremities. | |||
===Microscopic=== | ===Microscopic=== | ||
Features: | Features:<ref name=Ref_WMSP_613>{{Ref WMSP|613}}</ref> | ||
*Storiform pattern ([[AKA]] patternless pattern. | *Storiform pattern ([[AKA]] patternless pattern - '''key feature'''. | ||
*Marked nuclear pleomorphism. | *Marked nuclear pleomorphism '''key feature'''. | ||
**Variation is nuclear size, nuclear shape and nuclear staining (esp. hyperchromasia). | **Variation is nuclear size, nuclear shape and nuclear staining (esp. hyperchromasia). | ||
* | *Mitoses - abundant; atypical mitoses common. | ||
*Necrosis (common). | |||
*Mix of spindle cells and epithelioid cells. | |||
Other findings: | |||
*+/-Giant cells (see subclassification). | |||
*+/-Inflammation (see subclassification). | |||
**Neutrophils. | |||
**Eosinophils. | |||
====Subclassification==== | |||
UPS is subclassified the following way:<ref name=Ref_WMSP_613-4>{{Ref WMSP|613-4}}</ref> | |||
*UPS with giant cells. | |||
*UPS with inflammation. | |||
*UPS not otherwise specified (NOS) - wastebasket diagnosis; if neither of the above two apply. | |||
=Fibroblastic/myofibroblastic tumours= | =Fibroblastic/myofibroblastic tumours= | ||