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Difference between revisions of "Atypical fibroxanthoma"
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→Images: added a case of an important, albeit rare, diagnosis that can mimic AFX
(→Images: added a case of an important, albeit rare, diagnosis that can mimic AFX) |
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*[http://dermatology.cdlib.org/141/case_reports/afx/1.jpg AFX (cdlib.org)].<ref name=pmid18319023>{{Cite journal | last1 = Vandergriff | first1 = TW. | last2 = Reed | first2 = JA. | last3 = Orengo | first3 = IF. | title = An unusual presentation of atypical fibroxanthoma. | journal = Dermatol Online J | volume = 14 | issue = 1 | pages = 6 | month = | year = 2008 | doi = | PMID = 18319023 }}</ref> | *[http://dermatology.cdlib.org/141/case_reports/afx/1.jpg AFX (cdlib.org)].<ref name=pmid18319023>{{Cite journal | last1 = Vandergriff | first1 = TW. | last2 = Reed | first2 = JA. | last3 = Orengo | first3 = IF. | title = An unusual presentation of atypical fibroxanthoma. | journal = Dermatol Online J | volume = 14 | issue = 1 | pages = 6 | month = | year = 2008 | doi = | PMID = 18319023 }}</ref> | ||
A markedly atypical lesion of far less worrisome significance is the pleomorphic hyalinizing angioectatic tumor of soft parts (subcutis). | |||
[[File:DP27AP17 sl1.png| Pleomorphic hyalinizing angioectatic tumor of soft parts (subcutis).]] | |||
[[File:DP27AP17 sl2.png| Pleomorphic hyalinizing angioectatic tumor of soft parts (subcutis).]] | |||
[[File:DP27AP17 sl3.png| Pleomorphic hyalinizing angioectatic tumor of soft parts (subcutis).]] | |||
[[File:DP27AP17 sl4.png| Pleomorphic hyalinizing angioectatic tumor of soft parts (subcutis).]] | |||
[[File:DP27AP17 sl5.png| Pleomorphic hyalinizing angioectatic tumor of soft parts (subcutis).]] | |||
[[File:DP27AP17 sl6.png| Pleomorphic hyalinizing angioectatic tumor of soft parts (subcutis).]] | |||
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Pleomorphic hyalinizing angioectatic tumor of soft parts (subcutis). A. The key distinction is at low power, wherein cluters of thin-walled, indented (ectatic) blood vessels are seen. B. The ectatic vessels have a thin endothelial lining and a thick subjacent rim of amorphous eosinophilia. Note the multinucleated cells in the stroma. C. Hyaline material extends beyond vessels to entrap stromal cells. D. Cellularity in part raises the possibility of a sarcoma. E. High power further raises the suspicion of malignancy, given the aberrant nuclei with prominent nucleoli. F. Reassurance occurs because 1) there are virtually no mitoses, 2) there is no necrosis, and 3) there are readily identifiable nuclear inclusions as seen in these tumor cells. | |||
==IHC== | ==IHC== | ||