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Jensflorian (talk | contribs) (→Clear cell meningioma: +image) |
Jensflorian (talk | contribs) (SSTr2A DDx) |
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===DDx of meningioma & IHC<ref name=pmid16393681>{{cite journal |author=Hahn HP, Bundock EA, Hornick JL |title=Immunohistochemical staining for claudin-1 can help distinguish meningiomas from histologic mimics |journal=Am. J. Clin. Pathol. |volume=125 |issue=2 |pages=203–8 |year=2006 |month=February |pmid=16393681 |doi=10.1309/G659-FVVB-MG7U-4RPQ |url=http://ajcp.ascpjournals.org/content/125/2/203.full.pdf}}</ref>=== | ===DDx of meningioma & IHC<ref name=pmid16393681>{{cite journal |author=Hahn HP, Bundock EA, Hornick JL |title=Immunohistochemical staining for claudin-1 can help distinguish meningiomas from histologic mimics |journal=Am. J. Clin. Pathol. |volume=125 |issue=2 |pages=203–8 |year=2006 |month=February |pmid=16393681 |doi=10.1309/G659-FVVB-MG7U-4RPQ |url=http://ajcp.ascpjournals.org/content/125/2/203.full.pdf}}</ref>=== | ||
*S-100 +ve - [[schwannoma]]. | *S-100 strong +ve - [[schwannoma]]. | ||
**+ve in ~80% of fibrous meningiomas. | **+ve in ~80% of fibrous meningiomas. | ||
*CD34 +ve - [[solitary fibrous tumour]]. | *CD34 +ve - [[solitary fibrous tumour]]. | ||
**+ve in ~60% of [[fibrous meningioma]]s. | **+ve in ~60% of [[fibrous meningioma]]s. | ||
*STAT6 nuclear +ve: [[solitary fibrous tumour]]. | *STAT6 nuclear +ve: [[solitary fibrous tumour]]. | ||
*[[EMA]] +ve in ~30% of hemangiopericytoma. | *[[EMA]] +ve in ~30% of [[solitary fibrous tumour]]/[[hemangiopericytoma]]. | ||
*Claudin-1 - new kid on the block: +ve in meningioma, but low [[sensitivity]]. | *Claudin-1 - new kid on the block: +ve in meningioma, but low [[sensitivity]]. | ||
*SSTR2A +ve in meningioma, usu. -ve in [[Perineurioma]] <ref>{{Cite journal | last1 = Agaimy | first1 = A. | last2 = Buslei | first2 = R. | last3 = Coras | first3 = R. | last4 = Rubin | first4 = BP. | last5 = Mentzel | first5 = T. | title = Comparative study of soft tissue perineurioma and meningioma using a five-marker immunohistochemical panel. | journal = Histopathology | volume = 65 | issue = 1 | pages = 60-70 | month = Jul | year = 2014 | doi = 10.1111/his.12366 | PMID = 24393170 }}</ref> | |||
* Progesterone receptor: +ve in mostly grade I and meningeothelial tumors.<ref>{{Cite journal | last1 = Grunberg | first1 = SM. | title = The role of progesterone receptors in meningioma. | journal = Cancer Treat Res | volume = 58 | issue = | pages = 127-37 | month = | year = 1991 | doi = | PMID = 1683782 }}</ref> | * Progesterone receptor: +ve in mostly grade I and meningeothelial tumors.<ref>{{Cite journal | last1 = Grunberg | first1 = SM. | title = The role of progesterone receptors in meningioma. | journal = Cancer Treat Res | volume = 58 | issue = | pages = 127-37 | month = | year = 1991 | doi = | PMID = 1683782 }}</ref> | ||
* [[Pulmonary meningothelial-like nodule]] | * [[Pulmonary meningothelial-like nodule]] |