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Line 298: |
Line 298: |
| ***EWSR1-ATF1. | | ***EWSR1-ATF1. |
| ***EWSR1-CREB1 (GI tract associated). | | ***EWSR1-CREB1 (GI tract associated). |
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| ==Chondrosarcoma==
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| ===General===
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| *May arise from an ''enchondroma''.
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| *Usually a good prognosis.
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|
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| ===Microscopic===
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| Features:
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| *Resembles cartilage at low power.<ref name=Ref_Klatt417>{{Ref Klatt|417}}</ref>
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| *More cellular than cartilage... but relatively paucicellular compared to other sarcomas.
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|
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| Images:
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| *[http://commons.wikimedia.org/wiki/File:Chondrosarcoma_(1).jpg Chondrosarcoma - low mag. (WC)].
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| *[http://commons.wikimedia.org/wiki/File:Chondrosarcoma_(2).jpg Chondrosarcoma - high mag. (WC)].
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| *[http://commons.wikimedia.org/wiki/File:Chondrosarcoma_(3).jpg Chondrosarcoma - high mag. (WC)].
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|
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| DDx:
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| *[[Chordoma]].
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|
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| ====Grading====
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| Features:<ref name=Ref_WMSP643>{{Ref WMSP|643}}</ref>
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| *Grade I: moderate cellularity +/- binucleated cells.
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| *Grade III: nuclear pleomorphism, mitoses common.
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| *Grade II: between Grade I and Grade III.
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|
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| ===IHC===
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| *S-100 -ve. (???)
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|
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| ==Mesenchymal chondrosarcoma==
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| ===Microscopic===
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| Features:
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| *"White clouds in a blue sky".
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|
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| Image:
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| *[http://moon.ouhsc.edu/kfung/jty1/opaq/PathQuiz/S0A001-PQ01-M.htm Mesenchymal chondrosarcoma (ouhsc.edu)].
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| ==Synovial sarcoma== | | ==Synovial sarcoma== |