Difference between revisions of "Breast calcifications"

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(more formal)
 
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==General==
==General==
*Abnormal breast calcifications are considered a marker of [[malignancy]].
*Abnormal breast calcifications are considered a marker of [[malignancy]].
*Radiologists can pick-up calcifications that are approximately 100 micrometers; if "calcs" is on the requisition one needs to find calcifications this size.<ref>MUA. 1 October 2010.</ref>  
*Radiologists can pick-up calcifications that are approximately 100 micrometers; if "calcs" is on the requisition, the pathologist should be finding calcifications this size.<ref>MUA. 1 October 2010.</ref>  
**The large calcifications seen on radiology are approximately 1/5 - 1/6 the size of a HPF, if the field of view (FOV) is ~0.55 mm (as is the case with 22 mm-10x eye pieces and a 40x objective).
**The large calcifications seen on radiology are approximately 1/5 - 1/6 the size of a HPF, if the field of view (FOV) is ~0.55 mm (as is the case with 22 mm-10x eye pieces and a 40x objective).


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*Calcium phosphate - typically purple.
*Calcium phosphate - typically purple.
**Q. How to remember? A. '''P'''urple = '''P'''hosphate.
**Q. How to remember? A. '''P'''urple = '''P'''hosphate.
*Calcium oxalate - not associated with malignancy.<ref name=pmid26769216>{{Cite journal  | last1 = Sharma | first1 = T. | last2 = Radosevich | first2 = JA. | last3 = Pachori | first3 = G. | last4 = Mandal | first4 = CC. | title = A Molecular View of Pathological Microcalcification in Breast Cancer. | journal = J Mammary Gland Biol Neoplasia | volume =  | issue =  | pages =  | month = Jan | year = 2016 | doi = 10.1007/s10911-015-9349-9 | PMID = 26769216 }}</ref>  
*Calcium oxalate - not associated with malignancy.<ref name=pmid26769216>{{Cite journal  | last1 = Sharma | first1 = T. | last2 = Radosevich | first2 = JA. | last3 = Pachori | first3 = G. | last4 = Mandal | first4 = CC. | title = A Molecular View of Pathological Microcalcification in Breast Cancer. | journal = J Mammary Gland Biol Neoplasia | volume =  | issue =  | pages =  | month = Jan | year = 2016 | doi = 10.1007/s10911-015-9349-9 | PMID = 26769216 }}</ref>


==Microscopic==
==Microscopic==
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