Difference between revisions of "Goblet cell adenocarcinoma"

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==Microscopic==
==Microscopic==
Features:<ref name=pmid15967038>{{cite journal |author=Pahlavan PS, Kanthan R |title=Goblet cell carcinoid of the appendix |journal=World J Surg Oncol |volume=3 |issue= |pages=36 |year=2005 |month=June |pmid=15967038 |pmc=1182398 |doi=10.1186/1477-7819-3-36 |url=http://wjso.com/content/3/1/36}}</ref>
Features:<ref name=pmid15967038/>
*Mixed neuroendocrine-nonneuroendocrine tumour;<ref name=pmid17684764>{{cite journal |author=Volante M, Righi L, Asioli S, Bussolati G, Papotti M |title=Goblet cell carcinoids and other mixed neuroendocrine/nonneuroendocrine neoplasms |journal=Virchows Arch. |volume=451 Suppl 1 |issue= |pages=S61–9 |year=2007 |month=August |pmid=17684764 |doi=10.1007/s00428-007-0447-y |url=}}</ref> features of both ''carcinoid'' and ''adenocarcinoma.<ref name=pmid15967038/>
*Mixed neuroendocrine-nonneuroendocrine tumour;<ref name=pmid17684764>{{cite journal |author=Volante M, Righi L, Asioli S, Bussolati G, Papotti M |title=Goblet cell carcinoids and other mixed neuroendocrine/nonneuroendocrine neoplasms |journal=Virchows Arch. |volume=451 Suppl 1 |issue= |pages=S61–9 |year=2007 |month=August |pmid=17684764 |doi=10.1007/s00428-007-0447-y |url=}}</ref> features of both ''carcinoid'' and ''adenocarcinoma.<ref name=pmid15967038/>
**Archictecture: cells arranged in nests or clusters without a lumen.
**Archictecture: cells arranged in nests or clusters without a lumen.
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**Synaptophysin +ve.
**Synaptophysin +ve.
**Chromogranin +ve.
**Chromogranin +ve.
*S-100 +ve.
*[[S-100]] +ve.
*NSE +ve.
*NSE +ve.
*Serotonin +ve.
*Serotonin +ve.


Keratins:
Keratins:
*Usually CK20 +ve > CK7 +ve.
*Usually [[CK20]] +ve > [[CK7]] +ve.


*CEA +ve (membrane).
*CEA +ve (membrane).


Notes:
Notes:
*Nice review of stains in Pahlavan and Kanthan.<ref name=pmid15967038>{{cite journal |author=Pahlavan PS, Kanthan R |title=Goblet cell carcinoid of the appendix |journal=World J Surg Oncol |volume=3 |issue= |pages=36 |year=2005 |month=June |pmid=15967038 |pmc=1182398 |doi=10.1186/1477-7819-3-36 |url=http://wjso.com/content/3/1/36}}</ref>
*Review of stains in Pahlavan and Kanthan.<ref name=pmid15967038/>


==See also==
==See also==
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