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Difference between revisions of "Wilson's disease"
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*[[Steatosis of the liver|Steatosis]]. | *[[Steatosis of the liver|Steatosis]]. | ||
*Portal fibrosis. | *Portal fibrosis. | ||
[[File:1 Wilson 1 680x512px.tif|Inflamed & relatively unaffected segments (40X).]] | A. [[File:1 Wilson 1 680x512px.tif|Inflamed & relatively unaffected segments (40X).]]<br> | ||
[[File:2 Wilson 1 680x512px.tif|Bile ductular proliferation with interface hepatitis [inflammation of periportal hepatocytes] (200X).]] | B. [[File:2 Wilson 1 680x512px.tif|Bile ductular proliferation with interface hepatitis [inflammation of periportal hepatocytes] (200X).]]<br> | ||
<br> | C. [[File:3 Wilson 1 680x512px.tif|Enlarged hepatocytes, some with feathery degeneration, others with steatosis. Nuclei show nucleoli (400X).]]<br> | ||
[[File:3 Wilson 1 680x512px.tif|Enlarged hepatocytes, some with feathery degeneration, others with steatosis. Nuclei show nucleoli (400X).]] | D. [[File:4 Wilson 1 680x512px.tif|Trichrome shows periportal & sinusoidal fibrosis. No bridging was seen. (100X).]]<br> | ||
[[File:4 Wilson 1 680x512px.tif|Trichrome shows periportal & sinusoidal fibrosis. No bridging was seen. (100X).]] | Wilson’s disease, pre-cirrhotic. A. Inflamed & relatively unaffected segments. B. Bile ductular proliferation with interface hepatitis [inflammation of periportal hepatocytes]. C. Enlarged hepatocytes, some with feathery degeneration, others with steatosis. Nuclei show nucleoli. D. Trichrome shows periportal & sinusoidal fibrosis. | ||
Wilson’s disease, pre-cirrhotic. Inflamed & relatively unaffected segments | [[File:4 38555059990939 sl 1.png|Wilson’s disease with cirrhosis]] | ||
[[File:4 38555059990939 sl 2.png|Wilson’s disease with cirrhosis]] | |||
[[File:4 38555059990939 sl 3.png|Wilson’s disease with cirrhosis]] | |||
[[File:4 38555059990939 sl 4.png|Wilson’s disease with cirrhosis]] | |||
[[File:4 38555059990939 sl 5.png|Wilson’s disease with cirrhosis]] <br> | |||
Wilson’s disease with cirrhosis in a 22 year old woman. A. Nodules show steatosis without definite triads. B. Trichrome shows minute fibrous bound nodules in this case. C. Reticulin shows extensive regeneration (2-3 nuclei thick cords with lack of direction) with nodule formation. D. Bridge with extensive proliferated bile ductules and acute and chronic inflammatory cells. E. Ballooning degeneration with Mallory bodies. | |||
==Stains== | ==Stains== | ||