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Difference between revisions of "Liver metastasis"
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→Micro: add met thyroid carcinoma
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Metastatic poorly differentiated neuroendocrine carcinoma of pulmonary origin. Tumor presents as a mass (Row 1 Left 40X). Tumor replaces most of a triad; note the residual interlobular bile duct [arrow] (Row 1 Right 200X). Tumor cells mold, show scant cytoplasm, and marked anisonucleosis, larger than ordinary small cell carcinoma (Row 2 Left 400X). Tumor cells are positive for CK7 (Row 2 Right 400X). Tumor cells are positive for TTF1 (Row 3 Left 400X). Tumor cells are positive for CD56 (Row 3 Right 400X). | Metastatic poorly differentiated neuroendocrine carcinoma of pulmonary origin. Tumor presents as a mass (Row 1 Left 40X). Tumor replaces most of a triad; note the residual interlobular bile duct [arrow] (Row 1 Right 200X). Tumor cells mold, show scant cytoplasm, and marked anisonucleosis, larger than ordinary small cell carcinoma (Row 2 Left 400X). Tumor cells are positive for CK7 (Row 2 Right 400X). Tumor cells are positive for TTF1 (Row 3 Left 400X). Tumor cells are positive for CD56 (Row 3 Right 400X). | ||
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[[File:1 thyroid met 1 680x512px.tif| Metastatic thyroid carcinoma to liver]] | |||
[[File:2 thyroid met 1 680x512px.tif| Metastatic thyroid carcinoma to liver]] | |||
[[File:3 thyroid met 1 680x512px.tif| Metastatic thyroid carcinoma to liver]] | |||
[[File:4 thyroid met 1 680x512px.tif| Metastatic thyroid carcinoma to liver]] | |||
[[File:5 thyroid met 1 680x512px.tif| Metastatic thyroid carcinoma to liver]] | |||
[[File:6 thyroid met 1 680x512px.tif| Metastatic thyroid carcinoma to liver]] | |||
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Metastatic thyroid carcinoma. A. Carcinoma with open spaces spares part of a normal liver lobule [arrow] (40X). B. A sheet with acini [arrows] would indicate only adenocarcinoma (400X). C. A true papilla with vascular spaces [arrows] suggests papillary carcinoma (400X). D. Some spaces show tumor nuclei with inclusions [arrows] (400X). E. Tumor nuclei are TTF1 positive, which can also be seen with lung cancer (IHC 400X). F. Specific thyroglobulin positivity rendered the specific diagnosis known (IHC 400X). | |||