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Difference between revisions of "Dermal cysts"
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→EM, SJS, TEN: re-work
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(→EM, SJS, TEN: re-work) |
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*SJS and TEN are on a spectrum, EM is considered separate. | *SJS and TEN are on a spectrum, EM is considered separate. | ||
===Erythema multiforme | ===Erythema multiforme=== | ||
===Stevens-Johnson Syndrome | *Abbreviated ''EM''. | ||
====General==== | |||
Features:<ref name=Ref_PBoD8_1189>{{Ref PBoD8|1189}}</ref> | |||
*Hypersensitivity disorder to a drug or infections. | |||
**Assoc. with the following: HSV, Mycoplasma, Histoplasma, others. | |||
Clinical: | |||
*Target-like lesion. | |||
====Microscopic==== | |||
Features:<ref name=Ref_PBoD8_1189>{{Ref PBoD8|1189}}</ref> | |||
*Lymphocytic interface dermatitis (lymphocytes at the dermal-epidermal junction). | |||
*Necrotic/degenerative keratinocytes - '''key feature'''. | |||
*+/-Epidermal blistering. | |||
*+/-Epidermal sloughing. | |||
===Stevens-Johnson Syndrome=== | |||
*Abbreviated SJS. | |||
Rx causes of SJS: | Rx causes of SJS: | ||
*NSAIDs. | *NSAIDs. | ||
| Line 19: | Line 37: | ||
*Sulfonamides. | *Sulfonamides. | ||
*Penicillins. | *Penicillins. | ||
===Toxic Epidermal Necrolysis=== | |||
*Abbreviated TEN. | |||
TEN more severe form SJS. | TEN more severe form SJS. | ||