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Difference between revisions of "Alpha-1 antitrypsin deficiency"
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Alpha-1 antitrypsin deficiency (view source)
Revision as of 20:26, 6 September 2016
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Image:Alpha-1 antitrypsin deficiency.PAS Diastase.jpg | Alpha-1 AT deficiency - PASD. (WC/JMGardner) | Image:Alpha-1 antitrypsin deficiency.PAS Diastase.jpg | Alpha-1 AT deficiency - PASD. (WC/JMGardner) | ||
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[[File:1 A1AT 1 680x512px.tif| Alpha 1 Antitrypsin deficiency with cirrhosis]] | |||
[[File:2 A1AT 1 680x512px.tif| Alpha 1 Antitrypsin deficiency with cirrhosis]] | |||
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[[File:3 A1AT 1 680x512px.tif| Alpha 1 Antitrypsin deficiency with cirrhosis]] | |||
[[File:4 A1AT 1 680x512px.tif| Alpha 1 Antitrypsin deficiency with cirrhosis]] | |||
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[[File:5 A1AT 1 680x512px.tif| Alpha 1 Antitrypsin deficiency with cirrhosis]] | |||
[[File:6 A1AT 1 680x512px.tif| Alpha 1 Antitrypsin deficiency with cirrhosis]] | |||
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Alpha 1 Antitrypsin deficiency with cirrhosis. Dark inflamed bands bound hepatocyte nodules (Row 1 Left 40X). Steatosis afflicts some hepatocyte areas, within inflamed band lie proliferated bile ductules (Row 1 Right 100X). Reticulin shows regenerative (more than 2 nuclei per cord) nodules (black lines without definite directionality) amid bands (Row 2 Left 100X). Trichrome shows scar (Row 2 Right 100X). Hepatocytes show steatosis, foamy degeneration, and intranuclear inclusions (Row 3 Left 400X). PAS-D shows A1AT cytoplasmic granules; in non-A1AT cirrhosis, these granules would neither be in so many hepatocytes nor, in general, as large (Row 3 Right 400X). | |||
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*[http://moon.ouhsc.edu/kfung/jty1/opaq/pathquiz/l1k001-pq01.htm Alpha-1 AT (ouhsc.edu)]. | *[http://moon.ouhsc.edu/kfung/jty1/opaq/pathquiz/l1k001-pq01.htm Alpha-1 AT (ouhsc.edu)]. | ||