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Difference between revisions of "Non-malignant skin disease"
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m
→Dermatofibroma: +IHC
(→Syringoma: more) |
m (→Dermatofibroma: +IHC) |
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| Line 252: | Line 252: | ||
*AKA ''fibrous histiocytoma''. | *AKA ''fibrous histiocytoma''. | ||
*Reactive process -- it is ''not'' a neoplasm. | *Reactive process -- it is ''not'' a neoplasm. | ||
*Usually | *Usually associated with previous trauma. | ||
**In women... usually legs. | **In women... usually legs. | ||
| Line 271: | Line 271: | ||
*Neurofibroma. | *Neurofibroma. | ||
*Blue nevus. | *Blue nevus. | ||
*Dermatofibroma pertuberans (DFSP). | *[[Dermatofibroma pertuberans]] (DFSP). | ||
*Melanoma. | *[[Melanoma]]. | ||
===IHC=== | |||
Features:<ref name=pmid7694515>{{cite journal |author=Abenoza P, Lillemoe T |title=CD34 and factor XIIIa in the differential diagnosis of dermatofibroma and dermatofibrosarcoma protuberans |journal=Am J Dermatopathol |volume=15 |issue=5 |pages=429–34 |year=1993 |month=October |pmid=7694515 |doi= |url=}}</ref><ref name=pmid9129699>{{cite journal |author=Goldblum JR, Tuthill RJ |title=CD34 and factor-XIIIa immunoreactivity in dermatofibrosarcoma protuberans and dermatofibroma |journal=Am J Dermatopathol |volume=19 |issue=2 |pages=147–53 |year=1997 |month=April |pmid=9129699 |doi= |url=}}</ref> | |||
*Factor XIIIa +ve. | |||
**Usually negative in [[DFSP]]. | |||
*CD34 -ve. | |||
**Usually positive in DFSP. | |||
==Superficial dermal infiltrates== | ==Superficial dermal infiltrates== | ||