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Difference between revisions of "Tumour deposit"
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==General== | ==General== | ||
Significance: | |||
*Poor prognosticator. | |||
**Can be understood as a type of invasive front/border, e.g. ''well-circumscribed border'' versus ''infiltrative border''.<ref name=pmid24112678/> | |||
==Definition== | |||
Definition - TNM/AJCC 7th edition:<ref name=pmid21555695/> | Definition - TNM/AJCC 7th edition:<ref name=pmid21555695/> | ||
*Microscopic or macroscopic nodule in the lymphatic drainage bed of the tumour. | *Microscopic or macroscopic nodule in the lymphatic drainage bed of the tumour. | ||
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*#Irregular contour. | *#Irregular contour. | ||
*#*Round nodules of tumour are considered lymph nodes that are replaced by tumour. | *#*Round nodules of tumour are considered lymph nodes that are replaced by tumour. | ||
Notes: | Notes: | ||
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#>=2 mm from the tumour front. | #>=2 mm from the tumour front. | ||
#>=2 mm (radially) from the deepest aspect of the muscularis propria, if the tumour is not present in the plane of section. | #>=2 mm (radially) from the deepest aspect of the muscularis propria, if the tumour is not present in the plane of section. | ||
==Staging== | |||
Staging implications: | |||
*Tumour deposits are '''not''' counted as (positive) lymph nodes<ref name=pmid21555695>{{Cite journal | last1 = Nagtegaal | first1 = ID. | last2 = Tot | first2 = T. | last3 = Jayne | first3 = DG. | last4 = McShane | first4 = P. | last5 = Nihlberg | first5 = A. | last6 = Marshall | first6 = HC. | last7 = Påhlman | first7 = L. | last8 = Brown | first8 = JM. | last9 = Guillou | first9 = PJ. | title = Lymph nodes, tumor deposits, and TNM: are we getting better? | journal = J Clin Oncol | volume = 29 | issue = 18 | pages = 2487-92 | month = Jun | year = 2011 | doi = 10.1200/JCO.2011.34.6429 | PMID = 21555695 }}</ref> and in the context of positive lymph nodes do not change the [[Colorectal_cancer_staging#Nodal_stage|N stage]]. | |||
**If no positive lymph nodes are present, the N stage is pN1c. | |||
*The T stage is ''not'' affected by tumour deposits.<ref name=pmid21555695/> | |||
==See also== | ==See also== | ||