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Difference between revisions of "Cytokeratin 7"
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[[Image:Adenocarcinoma-Acinar type CK7 (5494540614).jpg| thumb|right|CK7 immunostain in acinar [[adenocarcinoma of the lung]].]] | [[Image:Adenocarcinoma-Acinar type CK7 (5494540614).jpg| thumb|right|CK7 immunostain in acinar [[adenocarcinoma of the lung]].]] | ||
'''Cytokeratin 7''', also '''keratin 7''' and '''CK7''', is a common low molecular keratin and a very common [[immunostain]].<ref name=pmid11007036>{{Cite journal | last1 = Chu | first1 = P. | last2 = Wu | first2 = E. | last3 = Weiss | first3 = LM. | title = Cytokeratin 7 and cytokeratin 20 expression in epithelial neoplasms: a survey of 435 cases. | journal = Mod Pathol | volume = 13 | issue = 9 | pages = 962-72 | month = Sep | year = 2000 | doi = 10.1038/modpathol.3880175 | PMID = 11007036 }}</ref> | '''Cytokeratin 7''', also '''keratin 7''' and '''CK7''', is a common low molecular keratin and a very common [[immunostain]].<ref name=pmid11007036>{{Cite journal | last1 = Chu | first1 = P. | last2 = Wu | first2 = E. | last3 = Weiss | first3 = LM. | title = Cytokeratin 7 and cytokeratin 20 expression in epithelial neoplasms: a survey of 435 cases. | journal = Mod Pathol | volume = 13 | issue = 9 | pages = 962-72 | month = Sep | year = 2000 | doi = 10.1038/modpathol.3880175 | PMID = 11007036 }}</ref> | ||
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* ‡ May be positive. In one series of head and neck SCC, conventional SCC: 7 +ve of 34 cases; [[basaloid squamous cell carcinoma]]: 24 +ve of 45 cases.<ref name=pmid20614292>{{Cite journal | last1 = Winters | first1 = R. | last2 = Naud | first2 = S. | last3 = Evans | first3 = MF. | last4 = Trotman | first4 = W. | last5 = Kasznica | first5 = P. | last6 = Elhosseiny | first6 = A. | title = Ber-EP4, CK1, CK7 and CK14 are useful markers for basaloid squamous carcinoma: a study of 45 cases. | journal = Head Neck Pathol | volume = 2 | issue = 4 | pages = 265-71 | month = Dec | year = 2008 | doi = 10.1007/s12105-008-0089-7 | PMID = 20614292 }}</ref> | * ‡ May be positive. In one series of head and neck SCC, conventional SCC: 7 +ve of 34 cases; [[basaloid squamous cell carcinoma]]: 24 +ve of 45 cases.<ref name=pmid20614292>{{Cite journal | last1 = Winters | first1 = R. | last2 = Naud | first2 = S. | last3 = Evans | first3 = MF. | last4 = Trotman | first4 = W. | last5 = Kasznica | first5 = P. | last6 = Elhosseiny | first6 = A. | title = Ber-EP4, CK1, CK7 and CK14 are useful markers for basaloid squamous carcinoma: a study of 45 cases. | journal = Head Neck Pathol | volume = 2 | issue = 4 | pages = 265-71 | month = Dec | year = 2008 | doi = 10.1007/s12105-008-0089-7 | PMID = 20614292 }}</ref> | ||
<gallery> | <gallery> | ||
File:Adenocarcinoma - CK7 immunostain (5762463282).jpg | Adenocarcinoma of the lung (WC/Yale Rosen) | File:Adenocarcinoma - CK7 immunostain (5762463282).jpg | Adenocarcinoma of the lung. (WC/Yale Rosen) | ||
File:Lymphoma - lung - CK7 -- intermed mag.jpg|Entrapped CK7-positive lung parenchyma within a lymphoma. (WC) | |||
</gallery> | </gallery> | ||