Difference between revisions of "Immunohistochemical staining"

Immunohistochemical staining (view source)

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 ==Keratins==
-Classification:<ref>[http://www.nordiqc.org/Epitopes/Cytokeratins/cytokeratins.htm http://www.nordiqc.org/Epitopes/Cytokeratins/cytokeratins.htm]</ref>
+{{Main|Keratins}}
-*Low molecular weight keratins (LMWK): [[CK7|7]], 8/18, [[CK19|19]], [[CK20|20]].
+Mark epithelial cells. Are typically seen in [[carcinoma]]s.
-*High molecular weight keratins (HWMK): 4, 10, 13, 14, 17.
-Uses:
-*CK8 ([[CAM5.2]])<ref>{{cite journal |author=Murata T, Nakashima Y, Takeuchi M, Sueishi K, Inomata H |title=The diagnostic use of low molecular weight keratin expression in sebaceous carcinoma |journal=Pathol. Res. Pract. |volume=189 |issue=8 |pages=888–93 |year=1993 |month=September |pmid=7508102 |doi= |url=}}</ref> - used to look for mets from breast cancer in axillary lymph nodes.
-*HWMK (e.g. K903<ref>URL: [http://www.aruplab.com/guides/ug/tests/2003978.jsp http://www.aruplab.com/guides/ug/tests/2003978.jsp]. Accessed on: 17 March 2011.</ref>) - [[squamous cell carcinoma]].
 ==Organ specific==