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Difference between revisions of "Pancreas"
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***Usually small as hormonally active. | ***Usually small as hormonally active. | ||
**Exocrine. | **Exocrine. | ||
===Pancreas neoplasms in a table=== | |||
{| class="wikitable" | |||
!| Type | |||
!| Key feature | |||
!| Subtypes | |||
!| Image | |||
!| IHC | |||
!| Detailed microscopic | |||
!| Usual location | |||
!| Other | |||
!| DDx | |||
|- | |||
| Serous tumours | |||
| cuboidal cells, clear cytoplasm | |||
| cystadenoma, borderline t., cystadenocarcinoma | |||
| Image? | |||
| IHC? | |||
| cuboidal cells, clear cytoplasm, central nucleus | |||
| body or tail | |||
| - | |||
| clear cell RCC, oligomucinous mucinous tumours | |||
|- | |||
| Intraductal papillary<br>mucinous tumour (IPMT) | |||
| mucin, no ovarian-like stroma | |||
| clear cell variant | |||
| Image? | |||
| IHC? | |||
| papillae, tall columnar mucin-producing cells | |||
| head | |||
| - | |||
| mucious neoplasms (other pancreatic, duodenal) | |||
|- | |||
| Mucinous tumour | |||
| mucin, ovarian-like stroma | |||
| cystadenoma, borderline t., cystadenocarcinoma | |||
| Image? | |||
| IHC? | |||
| tall columnar mucin-producing cells, ovarian-like stroma | |||
| body or tail | |||
| - | |||
| IPMT, metastatic mucinous tumours | |||
|- | |||
| Solid pseudopapillary<br>tumour | |||
| eosinophilic intracytoplasmic globules | |||
| clear cell variant (cytoplasm clear) | |||
| Image? | |||
| IHC | |||
| sheets of cells, focally loosely cohesive, eosinophilic cytoplasm, uniform nuclei with grooves | |||
| none | |||
| - | |||
| Ductal adenocarcinoma | |||
|- | |||
| Ductal adenocarcinoma | |||
| irregular shaped glands, cytologic atypia | |||
| mucinous, spindle cell, mixed ductal-endocrine | |||
| Image? | |||
| IHC? | |||
| glands, sheets, single cells, nuc. atypia, +/-mitoses, +/-necrosis | |||
| head | |||
| - | |||
| Ampullary carcinoma, chronic pancreatitis | |||
|} | |||
==Most important cystic lesions== | ==Most important cystic lesions== | ||