Difference between revisions of "Adrenal gland"

Adrenal gland (view source)

193 bytes added , 20:36, 19 March 2011

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 ==Anatomy & histology==
+===Histology===
+It is composed of a ''cortex'' and a ''medulla''.
+====Cortex====
+It has three layers - mnemonic: '''GFR''' (from superficial to deep):
+#Zona glomerulosa - salt (e.g. aldosterone).
+#*Eosinophilic cytoplasm. (???)
+#*Layer normally discontinuous.
+#Zona fasciculata - sugar (e.g. cortisol).
+#*Clear cytoplasm - '''key feature'''.
+#*Largest part of the cortex ~ 70%.
+#*Cells in cords/nests. (???)
+#Zona reticularis - steroid (e.g. dehydroepiandrosterone).
+#*Marked eosinophilia of cytoplasm - '''key feature'''.
+#*Granular/reticular cytoplasm.
+====Medulla====
+It consists of two cell types:<ref name=Ref_PBoD8_1159>{{Ref PBoD8|1159}}</ref>
+#Chromaffin cells.
+#*Arise of neural crest.
+#Sustentacular cells (supporting cells).
-===Histology===
+Produce ''NED'': norepinephrine, epinephrine, dopamine.
-Composed for ''cortex'' and medulla''.
-*Cortex has three layers - Mnemonic: '''GFR''' (from superficial to deep):
-**Zona glomerulosa - salt (e.g. aldosterone)
-***eosinophilic cytoplasm???
-***Normally discontinuous layer.
-**Zona fasciculata - sugar (e.g. cortisol)
-***Clear cytoplasm - '''key feature'''.
-***Largest part of the cortex ~ 70%.
-***Cells in cords/nests???
-**Zona reticularis - steroid (e.g. dehydroepiandrosterone).
-***Marked eosinophilia of cytoplasm - '''key feature'''.
-***Granular/reticular cytoplasm.
-*Medulla - produces ''NED'': norepinephrine, epinephrine, dopamine.
 ==Clinical==