Difference between revisions of "Medical liver disease"

Medical liver disease (view source)

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 ==Hepatitis B==
 :''Hepatitis B virus'', abbreviated ''HBV'', redirects here.
-===General===
+{{Main|Hepatitis B}}
-*May lead to [[hepatocellular carcinoma]] without [[cirrhosis]].
-*High prevalence.
-*Diagnosis is by serology.
-*A vaccination is available and done routinely in a many jurisdictions.<ref>{{Cite journal  | last1 = Leuridan | first1 = E. | last2 = Van Damme | first2 = P. | title = Hepatitis B and the need for a booster dose. | journal = Clin Infect Dis | volume = 53 | issue = 1 | pages = 68-75 | month = Jul | year = 2011 | doi = 10.1093/cid/cir270 | PMID = 21653306 }}</ref>
-Associated pathology:
-*[[Polyarteritis nodosa]] (PAN).
-*[[Membranoproliferative glomerulonephritis]].
-*[[Membranous nephropathy]].
-===Microscopic===
-Features:
-*Lobular inflammation - this is non-specific finding.
-**Hepatocyte necrosis:
-***Necrotic hepatocytes look a lot like neutrophils - however:
-****Cytoplasm is more pink.
-****Round apoptotic bodies.
-*[[Ground glass hepatocytes]] - '''important'''.
-DDx:
-*[[Hepatitis C]].
-*[[Autoimmune hepatitis]].
-*[[Primary biliary cirrhosis]] without [[granulomas]].
-*[[Drug-induced liver disease|Drug reaction]].
-====Image====
-<gallery>
-Image:Ground_glass_hepatocytes_high_mag_cropped_2.jpg | GGH - high mag. (WC)
-</gallery>
-===IHC===
-*[[Hepatitis B]] +ve.
 ==Hepatitis C==