Difference between revisions of "Leydig cell hyperplasia"

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*Benign.
*Benign.
*Uncommonly seen in isolation by pathology.
*Uncommonly seen in isolation by pathology.
*May be seen in the context of ''[[Klinefelter syndrome]]''.<ref name=pmid26209412>{{Cite journal  | last1 = Sterbis | first1 = J. | last2 = E-Nunu | first2 = T. | title = Leydig cell hyperplasia in the setting of Klinefelter syndrome. | journal = BMJ Case Rep | volume = 2015 | issue =  | pages =  | month =  | year = 2015 | doi = 10.1136/bcr-2015-209805 | PMID = 26209412 }}</ref>
 
A longer list of causes:<ref name=pmid9488073>{{Cite journal  | last1 = Naughton | first1 = CK. | last2 = Nadler | first2 = RB. | last3 = Basler | first3 = JW. | last4 = Humphrey | first4 = PA. | title = Leydig cell hyperplasia. | journal = Br J Urol | volume = 81 | issue = 2 | pages = 282-9 | month = Feb | year = 1998 | doi = 10.1046/j.1464-410X.1998.00503.x | PMID = 9488073 }}</ref>
*Congenital (primary).
*Secondary causes:
**Germ cell loss/decrease:
***[[Cryptorchism]].
***Advanced age.
**Endocrine-related:
***[[Adrenal hyperplasia]].
***Excess hCG (exogenous or tumour).
 
Other associations:<ref name=pmid9488073/>
*[[Kinefelter's syndrome]].<ref name=pmid26209412>{{Cite journal  | last1 = Sterbis | first1 = J. | last2 = E-Nunu | first2 = T. | title = Leydig cell hyperplasia in the setting of Klinefelter syndrome. | journal = BMJ Case Rep | volume = 2015 | issue =  | pages =  | month =  | year = 2015 | doi = 10.1136/bcr-2015-209805 | PMID = 26209412 }}</ref>
*Pernicious anemia.
*[[Alcoholism]].
*Infection - syphilis, tuberculosis.


==Gross==
==Gross==
48,830

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