Difference between revisions of "Pancreas"

Pancreas (view source)

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 ===General===
 *Obscure cell of origin.
-*Usually females (M:F=1:9).<ref>GLP. P.493.</ref>
+*Considered low grade, i.e. prognosis is usually good.
-*Mean age of presentation 35 years old.
+===Epidemiology===
+Features:<ref>GLP P.493.</ref>
+*Usually females (M:F=1:9).
+*Mean age of presentation third decade (20s).
 ===Management===
-Often followed radiologically:
+May be followed radiologically.
-*May be pseudocyst.
-*Often large.
+===Microscopic===
-*Solid.
+Features:<ref>GLP P.493-5.</ref>
-**Often has necrosis inside... creating spaces.
+*Solid sheets of cells, focally dyscohesive.
+*Eosinophilic cytoplasm.
+**Occasionally clear cytoplasm.<ref name=pmid18708424>{{cite journal |author=Serra S, Chetty R |title=Revision 2: an immunohistochemical approach and evaluation of solid pseudopapillary tumour of the pancreas |journal=J. Clin. Pathol. |volume=61 |issue=11 |pages=1153–9 |year=2008 |month=November |pmid=18708424 |doi=10.1136/jcp.2008.057828 |url=http://jcp.bmj.com/content/61/11/1153}}</ref>
+**Focal eosinophilic globules - '''key feature'''.
+*Uniform nuclei with occasional nuclear grooves.
+*+/-Necrosis - creating spaces/cavities.
+Image: [http://jcp.bmj.com/content/61/11/1153/F1.large.jpg Solid pseudopapillary tumour (bmj.com)].
+===DDx===
+*Pseudocyst.
+*Cystadenoma.
+*Cystadenocarcinoma.
 ==Carcinomas==