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Difference between revisions of "Autosomal dominant polycystic kidney disease"
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Autosomal dominant polycystic kidney disease (view source)
Revision as of 14:52, 21 June 2016
, 14:52, 21 June 2016no edit summary
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = | |||
| Width = | |||
| Caption = | |||
| Synonyms = | |||
| Micro = | |||
| Subtypes = | |||
| LMDDx = [[acquired cystic renal disease]] | |||
| Stains = | |||
| IHC = | |||
| EM = | |||
| Molecular = mutation in PKD1 gene or PKD2 gene | |||
| IF = | |||
| Gross = enlarged kidney composed to many cysts | |||
| Grossing = | |||
| Staging = | |||
| Site = [[kidney]] - see ''[[cystic kidney diseases]]'' | |||
| Assdx = [[end-stage kidney]], PKD1: [[cerebral aneurysm]]s; PKD2: [[diverticular disease|colonic diverticula]], [[aortic aneurysm]], [[mitral valve prolapse]] | |||
| Syndromes = | |||
| Clinicalhx = family member with polycystic kidney disease and | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = uncommon | |||
| Bloodwork = | |||
| Rads = polycystic kidneys | |||
| Endoscopy = | |||
| Prognosis = progressive renal failure | |||
| Other = | |||
| ClinDDx = | |||
| Tx = | |||
}} | |||
'''Autosomal dominant polycystic kidney disease''', abbreviated '''ADPKD''', is a common genetic cause of [[chronic renal failure]]. | '''Autosomal dominant polycystic kidney disease''', abbreviated '''ADPKD''', is a common genetic cause of [[chronic renal failure]]. | ||
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*Encodes polycystin. | *Encodes polycystin. | ||
*Death at ~53 years. | *Death at ~53 years. | ||
* | *Associated with cerebral aneurysms. | ||
PKD2 related disease:<ref name=Ref_MacSween174-5>{{Ref MacSween|174-5}}</ref> | PKD2 related disease:<ref name=Ref_MacSween174-5>{{Ref MacSween|174-5}}</ref> | ||