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Difference between revisions of "Necrobiotic xanthogranuloma"
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'''Necrobiotic xanthogranuloma''', abbreviated '''NXG''', is a rare [[granuloma|granulomatous]] [[skin]] condition. | |||
==General== | |||
*Usually elderly.<ref name=Ref_Derm629>{{Ref Derm|629}}</ref> | |||
==Gross== | |||
Features: | |||
*Periorbital - classic location.<ref name=pmid17544963>{{Cite journal | last1 = Fernández-Herrera | first1 = J. | last2 = Pedraz | first2 = J. | title = Necrobiotic xanthogranuloma. | journal = Semin Cutan Med Surg | volume = 26 | issue = 2 | pages = 108-13 | month = Jun | year = 2007 | doi = 10.1016/j.sder.2007.02.008 | PMID = 17544963 }}</ref> | |||
==Microscopic== | |||
Features:<ref name=Ref_Derm629>{{Ref Derm|629}}</ref> | |||
*"Necrobiotic granuloma": | |||
**Palisading granuloma with a core collagen-like material. | |||
*+/-Cholesterol clefts - common. | |||
*+/-[[Touton giant cell]]s. | |||
*+/-Atypical foreign body-type giant cells +/- asteroid bodies. | |||
DDx: | |||
*[[Granuloma annulare]]. | |||
*[[Necrobiosis lipoidica]] - has plasma cells. | |||
*Granuloma-forming infections - positive stains for microorganisms. | |||
===Image=== | |||
*[http://commons.wikimedia.org/wiki/File:Asteroid_bodies_high_mag_cropped.jpg Asteroid body (WC)]. | |||
==See also== | |||
*[[Inflammatory skin disorders]]. | |||
==References== | |||
{{Reflist|1}} | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||