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| ==Necrobiotic xanthogranuloma== | | ==Necrobiotic xanthogranuloma== |
| *Abbreviated ''NXG''. | | *Abbreviated ''NXG''. |
| ===General===
| | {{Main|Necrobiotic xanthogranuloma}} |
| *Usually elderly.<ref name=Ref_Derm629>{{Ref Derm|629}}</ref>
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| ===Gross===
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| Features:
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| *Periorbital - classic location.<ref name=pmid17544963>{{Cite journal | last1 = Fernández-Herrera | first1 = J. | last2 = Pedraz | first2 = J. | title = Necrobiotic xanthogranuloma. | journal = Semin Cutan Med Surg | volume = 26 | issue = 2 | pages = 108-13 | month = Jun | year = 2007 | doi = 10.1016/j.sder.2007.02.008 | PMID = 17544963 }}</ref>
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| ===Microscopic===
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| Features:<ref name=Ref_Derm629>{{Ref Derm|629}}</ref>
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| *"Necrobiotic granuloma":
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| **Palisading granuloma with a core collagen-like material.
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| *+/-Cholesterol clefts - common.
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| *+/-[[Touton giant cell]]s.
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| *+/-Atypical foreign body-type giant cells +/- asteroid bodies.
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| DDx:
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| *[[Granuloma annulare]].
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| *[[Necrobiosis lipoidica]] - has plasma cells.
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| *Granuloma-forming infections - positive stains for microorganisms.
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| Image:
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| *[http://commons.wikimedia.org/wiki/File:Asteroid_bodies_high_mag_cropped.jpg Asteroid body (WC)].
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| =DDx for pattern= | | =DDx for pattern= |