Difference between revisions of "Steatohepatitis"

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→‎Grading steatohepatitis: templating reference
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===Grading steatohepatitis===
===Grading steatohepatitis===
Grading inflammation:<ref name=pmid10484010>Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions. Brunt EM, Janney CG, Di Bisceglie AM, Neuschwander-Tetri BA, Bacon BR. Am J Gastroenterol. 1999 Sep;94(9):2467-74. PMID 10484010.</ref>
Grading inflammation:<ref name=pmid10484010>{{Cite journal  | last1 = Brunt | first1 = EM. | last2 = Janney | first2 = CG. | last3 = Di Bisceglie | first3 = AM. | last4 = Neuschwander-Tetri | first4 = BA. | last5 = Bacon | first5 = BR. | title = Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions. | journal = Am J Gastroenterol | volume = 94 | issue = 9 | pages = 2467-74 | month = Sep | year = 1999 | doi = 10.1111/j.1572-0241.1999.01377.x | PMID = 10484010 }}ref>
*Grade 1 - steatosis, occasional ballooning degeneration, PMNs.
*Grade 1 - steatosis, occasional ballooning degeneration, PMNs.
*Grade 2 - obvious ballooning, obvious PMNs, chronic inflammation.
*Grade 2 - obvious ballooning, obvious PMNs, chronic inflammation.
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Necroinflammatory grades Brunt 3, NAH 8. Fibrosis stage 4. Steatosis is pan-acinar (UL). Acinar inflammatory aggregates More than 4 inflammatory aggregates are seen in a 20X field (UR black arrowheads). Many cells show ballooning degeneration, with tufts/flocks of material cytoplasm (LL yellow arrowheads) Trichrome limns regenerative nodules (LR magenta arrowheads). Original oculars UL 4X,  UR 20X, LL 40X (higher pixel photograph), LR 10X
Necroinflammatory grades Brunt 3, NAH 8. Fibrosis stage 4. Steatosis is pan-acinar (UL). Acinar inflammatory aggregates More than 4 inflammatory aggregates are seen in a 20X field (UR black arrowheads). Many cells show ballooning degeneration, with tufts/flocks of material cytoplasm (LL yellow arrowheads) Trichrome limns regenerative nodules (LR magenta arrowheads). Original oculars UL 4X,  UR 20X, LL 40X (higher pixel photograph), LR 10X


===Image===
===Image===
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