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Difference between revisions of "Adrenal gland"
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→Microscopic: more
(→Adrenocortical carcinoma: +IHC) |
(→Microscopic: more) |
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#Adrenal sinusoid invasion; lymphovascular space invasion within the adrenal gland. | #Adrenal sinusoid invasion; lymphovascular space invasion within the adrenal gland. | ||
#Capsular invasion. | #Capsular invasion. | ||
A simplified set of criteria by ''Volante et al.''<ref name=pmid19912359>{{cite journal |author=Volante M, Bollito E, Sperone P, ''et al.'' |title=Clinicopathological study of a series of 92 adrenocortical carcinomas: from a proposal of simplified diagnostic algorithm to prognostic stratification |journal=Histopathology |volume=55 |issue=5 |pages=535–43 |year=2009 |month=November |pmid=19912359 |doi=10.1111/j.1365-2559.2009.03423.x |url=}}</ref> also exist: | |||
#Reticular network disruption - with reticulin staining. | |||
#One of the following: | |||
##Abundant mitoses >5/50 high-power fields (HPF). | |||
##Necrosis. | |||
##Vascular invasion. | |||
Image: | Image: | ||
*[http://commons.wikimedia.org/wiki/File:Adrnal_cortical_carcinoma.JPG ACC (AFIP/WC)]. | *[http://commons.wikimedia.org/wiki/File:Adrnal_cortical_carcinoma.JPG ACC (AFIP/WC)]. | ||
Notes: | |||
*Tumour may contain fat.<ref name=pmid15688105>{{cite journal |author=Heye S, Woestenborghs H, Van Kerkhove F, Oyen R |title=Adrenocortical carcinoma with fat inclusion: case report |journal=Abdom Imaging |volume=30 |issue=5 |pages=641–3 |year=2005 |pmid=15688105 |doi=10.1007/s00261-004-0281-5 |url=}}</ref> | |||
===IHC=== | ===IHC=== | ||