Difference between revisions of "Lymph node metastasis"

Lymph node metastasis (view source)

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 ==Staging==
+It is customary to record:
+# The size of the largest lymph node metastasis.‡
+#* It is a dictum of the ''Association of Directors of Anatomic and Surgical pathology''<ref name=pmid11007046>{{Cite journal  | title = Recommendations for the reporting of specimens containing oral cavity and oropharynx neoplasms. | journal = Mod Pathol | volume = 13 | issue = 9 | pages = 1038-41 | month = Sep | year = 2000 | doi = 10.1038/modpathol.3880188 | PMID = 11007046 }}</ref> that masses >3 cm are matted lymph nodes/confluent lymph nodes ''or'' a tumour mass.
+# The presence/absence of extranodal extension.
+#* Tumour grows into the surrounding fat ''or'' extends beyond the contour of the lymph node in association with [[desmoplasia]].
+Note:
+*‡ Large size is considered significant at some anatomical [[site]]s, e.g. pharynx. It may changes the N stage.
+===Number of lymph nodes===
 *The number of lymph nodes is important for [[staging]], as a small number may lead to stage migration (Will Rogers phenomenon);<ref name=pmid24744586>{{Cite journal  | last1 = Deng | first1 = JY. | last2 = Liang | first2 = H. | title = Clinical significance of lymph node metastasis in gastric cancer. | journal = World J Gastroenterol | volume = 20 | issue = 14 | pages = 3967-75 | month = Apr | year = 2014 | doi = 10.3748/wjg.v20.i14.3967 | PMID = 24744586 }}</ref> thus, the number of lymph nodes is often used as a [[quality]] measure.