Difference between revisions of "Lymph node pathology"

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==Langerhans cell histiocytosis==
==Langerhans cell histiocytosis==
===General===
{{Main|Langerhans cell histiocytosis}}
*Abbreviated ''LCH''.
*Genetic thingy.
*Looks like eosinophilic granuloma of the lung - see ''[[Medical_lung_diseases#Pulmonary_Langerhans_cell_histiocytosis|medical lung diseases]]''.


===Microscopic===
===Microscopic===
Features:
Features:
*Langerhans cells histiocytes:
*Langerhans cells histiocytes - '''key feature'''.
**Clusters of cells (histiocytes) with a reniform (kidney-shaped) nucleus and abundant foamy cytoplasm.
**Clusters of cells (histiocytes) with a reniform (kidney-shaped) nucleus and abundant foamy cytoplasm.
**+/-Eosinophils - often prominent.


Images:
See ''[[Langerhans cell histiocytosis]]'' for details.
*[http://commons.wikimedia.org/wiki/File:Langerhans_cell_histiocytosis_-_very_high_mag.jpg LCH - lymph node - very high mag. (WC)].
*[http://commons.wikimedia.org/wiki/File:Langerhans_cell_histiocytosis_-_high_mag.jpg LCH - lymph node - high mag. (WC)].
 
===IHC===
*CD1a +ve.
*S100 +ve.


==See also==
==See also==
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