Difference between revisions of "TFEB-rearranged renal cell carcinoma"

TFEB-rearranged renal cell carcinoma (view source)

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 ==IHC==
 *TFEB +ve (nuclear staining).
-*HMB-45 +ve<ref name=pmid24877033/> (focal<ref name=pmid12719541/>).
 *TFE3 -ve.
+*Melan A +ve (13 +ve of 13 cases<ref name=pmid24618616>{{Cite journal  | last1 = Smith | first1 = NE. | last2 = Illei | first2 = PB. | last3 = Allaf | first3 = M. | last4 = Gonzalez | first4 = N. | last5 = Morris | first5 = K. | last6 = Hicks | first6 = J. | last7 = Demarzo | first7 = A. | last8 = Reuter | first8 = VE. | last9 = Amin | first9 = MB. | title = t(6;11) renal cell carcinoma (RCC): expanded immunohistochemical profile emphasizing novel RCC markers and report of 10 new genetically confirmed cases. | journal = Am J Surg Pathol | volume = 38 | issue = 5 | pages = 604-14 | month = May | year = 2014 | doi = 10.1097/PAS.0000000000000203 | PMID = 24618616 }}</ref>).
+*HMB-45 +ve (12 +ve of 13 cases<ref name=pmid24618616/>)
+*PAX8 +ve/-ve (14 +ve of 23<ref name=pmid24618616/>).
+*CAM5.2 +ve (8 +ve of 13<ref name=pmid24618616/>).
+*RCC +ve (10 +ve of 14<ref name=pmid24618616/>).
+*CD10 +ve (10 +ve of 14<ref name=pmid24618616/>).
 ==Molecular==