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Gastric heterotopia of the duodenum (view source)
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# | '''Gastric heterotopia of the duodenum''' is a relatively common finding of the [[duodenum]]. | ||
==General== | |||
*Common ~15% of cases in one series.<ref name=pmid22295146>{{Cite journal | last1 = Terada | first1 = T. | title = Pathologic observations of the duodenum in 615 consecutive duodenal specimens: I. benign lesions. | journal = Int J Clin Exp Pathol | volume = 5 | issue = 1 | pages = 46-51 | month = | year = 2012 | doi = | PMID = 22295146 }}</ref> | |||
*Probably not related to [[Helicobacter pylori]].<ref name=pmid20656325>{{Cite journal | last1 = Genta | first1 = RM. | last2 = Kinsey | first2 = RS. | last3 = Singhal | first3 = A. | last4 = Suterwala | first4 = S. | title = Gastric foveolar metaplasia and gastric heterotopia in the duodenum: no evidence of an etiologic role for Helicobacter pylori. | journal = Hum Pathol | volume = 41 | issue = 11 | pages = 1593-600 | month = Nov | year = 2010 | doi = 10.1016/j.humpath.2010.04.010 | PMID = 20656325 }}</ref> | |||
==Gross== | |||
*Typically nodules/polyps.<ref name=pmid6840712>{{Cite journal | last1 = Shousha | first1 = S. | last2 = Spiller | first2 = RC. | last3 = Parkins | first3 = RA. | title = The endoscopically abnormal duodenum in patients with dyspepsia: biopsy findings in 60 cases. | journal = Histopathology | volume = 7 | issue = 1 | pages = 23-34 | month = Jan | year = 1983 | doi = | PMID = 6840712 }}</ref> | |||
==Microscopic== | |||
Features: | |||
#Foveolar epithelium. | |||
#Gastric glands - body-type or antral-type. | |||
DDx: | |||
*Foveolar metaplasia (isolated) - see [[chronic duodenitis]]. | |||
*Foveolar gastric-type dysplasia.<ref>{{Cite journal | last1 = Park | first1 = do Y. | last2 = Srivastava | first2 = A. | last3 = Kim | first3 = GH. | last4 = Mino-Kenudson | first4 = M. | last5 = Deshpande | first5 = V. | last6 = Zukerberg | first6 = LR. | last7 = Song | first7 = GA. | last8 = Lauwers | first8 = GY. | title = Adenomatous and foveolar gastric dysplasia: distinct patterns of mucin expression and background intestinal metaplasia. | journal = Am J Surg Pathol | volume = 32 | issue = 4 | pages = 524-33 | month = Apr | year = 2008 | doi = 10.1097/PAS.0b013e31815b890e | PMID = 18300795 }}</ref> | |||
===Images=== | |||
<gallery> | |||
Image: Gastric heterotopia in the duodenum -- low mag.jpg | GH - low mag. (WC) | |||
Image: Gastric heterotopia in the duodenum -- intermed mag.jpg | GH - intermed. mag. (WC) | |||
Image: Gastric heterotopia in the duodenum -- high mag.jpg | GH - high mag. (WC) | |||
</gallery> | |||
www: | |||
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267485/figure/fig03/ Gastric heterotopia (nih.gov)].<ref name=pmid22295146>{{Cite journal | last1 = Terada | first1 = T. | title = Pathologic observations of the duodenum in 615 consecutive duodenal specimens: I. benign lesions. | journal = Int J Clin Exp Pathol | volume = 5 | issue = 1 | pages = 46-51 | month = | year = 2012 | doi = | PMID = 22295146 }}</ref> | |||
==Sign out== | |||
<pre> | |||
DUODENUM, BIOPSY: | |||
- SMALL BOWEL MUCOSA WITH GASTRIC (BODY-TYPE) HETEROTOPIA. | |||
- NEGATIVE FOR SIGNIFICANT PATHOLOGY. | |||
</pre> | |||
===Alternate=== | |||
<pre> | |||
DUODENUM, BIOPSY: | |||
- SMALL BOWEL MUCOSA AND BRUNNER'S GLANDS WITHIN NORMAL LIMITS. | |||
- GASTRIC HETEROTOPIA, BODY-TYPE MUCOSA. | |||
</pre> | |||
==See also== | |||
*[[Duodenum]]. | |||
*[[Stomach]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Duodenum]] | |||