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Difference between revisions of "Polarization"
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[[Image:Acquired_cystic_disease-associated_renal_cell_carcinoma_-2a--_intermed_mag.gif|thumb|right|[[Acquired cystic disease-associated renal cell carcinoma]] with non-polarized light and polarized light to highlight the oxylate crystals. [[H&E stain]].]] | [[Image:Gout - monosodium urate crystals (20X, polarized, red compensator).jpg|thumb|right|Crystals ([[gout]]) and blood cells in polarized light. (WC/Gabriel Caponetti)]] | ||
[[Image:Acquired_cystic_disease-associated_renal_cell_carcinoma_-2a--_intermed_mag.gif|thumb|right|[[Acquired cystic disease-associated renal cell carcinoma]] with non-polarized light and polarized light to highlight the oxylate crystals. [[H&E stain]]. (WC/Nephron)]] | |||
'''Polarization''', formally '''light polarization''', in [[pathology]] refers to a technique used in [[light microscopy]] that makes use of polarized light. | '''Polarization''', formally '''light polarization''', in [[pathology]] refers to a technique used in [[light microscopy]] that makes use of polarized light. | ||
== | ==General== | ||
*Polarization is a useful characteristic as it is only seen in handful of pathologies. | |||
*In some cases the colour and histomorphology can be specific enough to be diagnostic. | |||
==Notable things that polarize== | |||
*[[Amyloid]] - apple-green birefringence.<ref name=pmid26485243>{{Cite journal | last1 = Cornejo | first1 = KM. | last2 = Lagana | first2 = FJ. | last3 = Deng | first3 = A. | title = Nodular amyloidosis derived from keratinocytes: an unusual type of primary localized cutaneous nodular amyloidosis. | journal = Am J Dermatopathol | volume = 37 | issue = 11 | pages = e129-33 | month = Nov | year = 2015 | doi = 10.1097/DAD.0000000000000307 | PMID = 26485243 }}</ref> | *[[Amyloid]] - apple-green birefringence.<ref name=pmid26485243>{{Cite journal | last1 = Cornejo | first1 = KM. | last2 = Lagana | first2 = FJ. | last3 = Deng | first3 = A. | title = Nodular amyloidosis derived from keratinocytes: an unusual type of primary localized cutaneous nodular amyloidosis. | journal = Am J Dermatopathol | volume = 37 | issue = 11 | pages = e129-33 | month = Nov | year = 2015 | doi = 10.1097/DAD.0000000000000307 | PMID = 26485243 }}</ref> | ||
*Oxylate crystals | *Oxylate crystals. | ||
**[[Ethylene glycol poisoning]].<ref name=pmid19874660>{{Cite journal | last1 = Rosano | first1 = TG. | last2 = Swift | first2 = TA. | last3 = Kranick | first3 = CJ. | last4 = Sikirica | first4 = M. | title = Ethylene glycol and glycolic acid in postmortem blood from fatal poisonings. | journal = J Anal Toxicol | volume = 33 | issue = 8 | pages = 508-13 | month = Oct | year = 2009 | doi = | PMID = 19874660 }}</ref> | |||
**[[Acquired cystic disease-associated renal cell carcinoma]]. | |||
**Benign [[breast calcifications]].<ref name=pmid10097726>{{Cite journal | last1 = Ozer | first1 = E. | last2 = Canda | first2 = T. | last3 = Balci | first3 = P. | last4 = Gökçe | first4 = O. | title = Calcium oxalate crystals in benign cyst fluid from the breast. A case report. | journal = Acta Cytol | volume = 43 | issue = 2 | pages = 281-4 | month = | year = | doi = | PMID = 10097726 }}</ref> | |||
*[[Gout]] crystals - negatively birefringent, yellow when aligned, needle-shaped.<ref name=Ref_TN2005>{{Ref TN2005| RH6}}</ref> | |||
*[[Pseudogout]] crystals - positively birefringent, blue when aligned, rhomboid-shaped.<ref name=Ref_TN2005>{{Ref TN2005| RH6}}</ref> | |||
==Some other things that polarize== | |||
*Dirt. | |||
*Collagen. | |||
==See also== | ==See also== | ||
| Line 11: | Line 25: | ||
==References== | ==References== | ||
{{Reflist| | {{Reflist|2}} | ||
==External links== | |||
*[https://en.wikipedia.org/wiki/Birefringence Birefringence (wikipedia.org)]. | |||
[[Category:Basics]] | [[Category:Basics]] | ||