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Difference between revisions of "Oncocytoma of the salivary gland"
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Oncocytoma of the salivary gland (view source)
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'''Oncocytoma of the salivary gland''' is a rare benign tumour of the [[salivary glands]]. | {{ Infobox diagnosis | ||
| Name = {{PAGENAME}} | |||
| Image = Parotid_gland_oncocytoma_-_very_high_mag.jpg | |||
| Width = | |||
| Caption = Salivary gland oncocytoma. [[H&E stain]]. (WC/Nephron) | |||
| Synonyms = salivary gland oncocytoma | |||
| Micro = abundant eosinophilic cytoplasm; architecture: solid, trabecular or duct-like | |||
| Subtypes = | |||
| LMDDx = [[acinic cell carcinoma]], metastatic [[renal cell carcinoma]], oncocytic carcinoma | |||
| Stains = | |||
| IHC = p63 +ve | |||
| EM = increased numbers of mitochondria | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Staging = | |||
| Site = [[salivary gland]] | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = very rare | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = benign | |||
| Other = | |||
| ClinDDx = other salivary gland tumours | |||
| Tx = | |||
}} | |||
'''Oncocytoma of the salivary gland''' (also '''salivary gland oncocytoma''') is a rare benign tumour of the [[salivary glands]]. | |||
==General== | ==General== | ||
*No risk of malignant transformation. | *No risk of malignant transformation. | ||
*Rare ~20 reported in literature.<ref>{{cite journal |author=Uzunkulaoğlu H, Yazici H, Can IH, Doğan S, Uzunkulaoğlu T |title=Bilateral oncocytoma in the parotid gland |journal=J Craniofac Surg |volume=23 |issue=3 |pages=e246–7 |year=2012 |month=May |pmid=22627459 |doi=10.1097/SCS.0b013e31824dfccd |url=}}</ref> | *Rare ~20 reported in literature.<ref name=pmid22627459>{{cite journal |author=Uzunkulaoğlu H, Yazici H, Can IH, Doğan S, Uzunkulaoğlu T |title=Bilateral oncocytoma in the parotid gland |journal=J Craniofac Surg |volume=23 |issue=3 |pages=e246–7 |year=2012 |month=May |pmid=22627459 |doi=10.1097/SCS.0b013e31824dfccd |url=}}</ref> | ||
*Thought to be ~1% of all salivary gland tumours. | *Thought to be ~1% of all salivary gland tumours. | ||
*Typical age: 60s-80s. | *Typical age: 60s-80s. | ||
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Features: | Features: | ||
*Like [[oncocytoma]]s elsewhere. | *Like [[oncocytoma]]s elsewhere. | ||
** | **Abundant eosinophilic cytoplasm (on [[H&E stain]]). | ||
***Due to increased number of mitochrondria. | ***Due to increased number of mitochrondria. | ||
**Fine capillaries. | **Fine capillaries. | ||
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DDx: | DDx: | ||
*[[Acinic cell carcinoma]]. | *[[Acinic cell carcinoma]]. | ||
*Metastatic [[renal cell carcinoma]] - esp. [[chromophobe renal cell carcinoma]]. | |||
*Oncocytic carcinoma. | |||
===Images=== | ===Images=== | ||