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Difference between revisions of "Neuroendocrine neoplasms"
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Neuroendocrine neoplasms (view source)
Revision as of 19:55, 5 December 2023
, 19:55, 5 December 2023no edit summary
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DDx: | DDx: | ||
*[[Paraganglioma]]. | *[[Paraganglioma]]. | ||
*Neoplasm with neuroendocrine differentiation (<30% neuroendocrine component<ref name=pmid26556999>{{Cite journal | last1 = Kleist | first1 = B. | last2 = Poetsch | first2 = M. | title = Neuroendocrine differentiation: The mysterious fellow of colorectal cancer. | journal = World J Gastroenterol | volume = 21 | issue = 41 | pages = 11740-7 | month = Nov | year = 2015 | doi = 10.3748/wjg.v21.i41.11740 | PMID = 26556999 }}</ref>). | |||
==Images== | ==Images== | ||
| Line 55: | Line 56: | ||
*NSE +ve. | *NSE +ve. | ||
*[[CD56]] +ve. | *[[CD56]] +ve. | ||
*Ki-67 - useful for grading. | *[[Ki-67]] - useful for grading. | ||
*PGP9.5.<ref name=pmid20182342/> | *PGP9.5.<ref name=pmid20182342/> | ||
*CDX2 -ve/+ve. | *[[CDX2]] -ve/+ve. | ||
**+ve suggests ileum, appendix or colon origin.<ref name=pmid22180832>{{Cite journal | last1 = Saad | first1 = RS. | last2 = Ghorab | first2 = Z. | last3 = Khalifa | first3 = MA. | last4 = Xu | first4 = M. | title = CDX2 as a marker for intestinal differentiation: Its utility and limitations. | journal = World J Gastrointest Surg | volume = 3 | issue = 11 | pages = 159-66 | month = Nov | year = 2011 | doi = 10.4240/wjgs.v3.i11.159 | PMID = 22180832 }}</ref> | **+ve suggests ileum, appendix or colon origin.<ref name=pmid22180832>{{Cite journal | last1 = Saad | first1 = RS. | last2 = Ghorab | first2 = Z. | last3 = Khalifa | first3 = MA. | last4 = Xu | first4 = M. | title = CDX2 as a marker for intestinal differentiation: Its utility and limitations. | journal = World J Gastrointest Surg | volume = 3 | issue = 11 | pages = 159-66 | month = Nov | year = 2011 | doi = 10.4240/wjgs.v3.i11.159 | PMID = 22180832 }}</ref> | ||
*Serotonin -ve/+ve. | |||
**+ve suggests jejuno-ileal origin.{{fact}} | |||
Hormone products: | Hormone products: | ||
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*[[Basics]]. | *[[Basics]]. | ||
*[[Goblet cell carcinoid]]. | *[[Goblet cell carcinoid]]. | ||
*[[Mixed neuroendocrine-nonneuroendocrine neoplasm]] (MiNEN). | |||
=References= | =References= | ||