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Difference between revisions of "Serous borderline tumour"
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'''Serous borderline tumour''' is a Muellerian epithelial [[ovarian tumour]] with a behaviour that borders on [[malignant]]. | |||
It is also known as '''serous ovarian tumour of low malignant potential'''.<ref name=pmid10881733/> | |||
==General== | |||
*Usually benign. | |||
*Require long term follow-up. | |||
==Microscopic== | |||
Features:<ref name=Ref_GP399>{{Ref GP|399}}</ref> | |||
*Cuboidal to columnar epithelium with mild to moderate atypia. | |||
*No invasive. | |||
*"Sparse" mitoses. | |||
*+/-[[Psammoma bodies]]. | |||
*+/-Micropapillary architecture - often described as a ''medusa head'' pattern. | |||
DDx: | |||
*[[Serous carcinoma of the ovary]] - focus a with stromal invasion >5mm (linear measurement) ''or'' > 10 mm<sup>2</sup> (area).<ref name=Ref_GP399>{{Ref GP|399}}</ref> | |||
**Invasive cells are "pink", i.e. have abundant eosinophilic cytoplasm,<ref name=Ref_GP399/>; also, cells usu. large (~2-3x size of non-invasive component), and typically have an enlarged nucleus (~2x non-invasive component). | |||
*[[Clear cell carcinoma of the ovary]] - classically associated with [[endometriosis]], have simpler, smaller papillae without branching. | |||
Images: | |||
*[http://pubs.rsna.org/na101/home/literatum/publisher/rsna/journals/content/radiographics/2005/radiographics.2005.25.issue-6/rg.256055015/production/images/medium/g05nv16c4x.jpeg Serous ovarian LMP tumour (radiographics.rsna.org)].<ref name=pmid16284143>{{Cite journal | last1 = Burkholz | first1 = KJ. | last2 = Wood | first2 = BP. | last3 = Zuppan | first3 = C. | title = Best cases from the AFIP: Borderline papillary serous tumor of the right ovary. | journal = Radiographics | volume = 25 | issue = 6 | pages = 1689-92 | month = | year = | doi = 10.1148/rg.256055015 | PMID = 16284143 }}</ref> | |||
===Subclassification=== | |||
Typical subdivided into:<ref name=pmid21917305>{{Cite journal | last1 = Park | first1 = JY. | last2 = Kim | first2 = DY. | last3 = Kim | first3 = JH. | last4 = Kim | first4 = YM. | last5 = Kim | first5 = KR. | last6 = Kim | first6 = YT. | last7 = Nam | first7 = JH. | title = Micropapillary pattern in serous borderline ovarian tumors: does it matter? | journal = Gynecol Oncol | volume = 123 | issue = 3 | pages = 511-6 | month = Dec | year = 2011 | doi = 10.1016/j.ygyno.2011.08.008 | PMID = 21917305 }}</ref> | |||
*Micropapillary serous borderline tumour. | |||
*Typical serous borderline tumour (SBOT). | |||
==Sign out== | |||
<pre> | |||
Cyst and Right Fallopian Tube, Excision: | |||
- SEROUS BORDERLINE TUMOUR with micropapillary architecture, see comment. | |||
- Fallopian tube within normal limits. | |||
- NEGATIVE for evidence of invasion. | |||
Comment: | |||
The lesion appears to be confined to a cystic structure. | |||
</pre> | |||
==See also== | |||
*[[Ovarian tumours]]. | |||
==References== | |||
{{Reflist|1}} | |||
[[Category:Diagnosis]] | |||
[[Category:Ovarian tumours]] | |||